Téllez-Castillo Carlos J, Müller Lukas, Rekendt Ann-Katrin, Pra-Mio Laura, Scharmann Claas
Praxis für Labormedizin und Mikrobiologie, Bochum, Germany.
Rev Esp Quimioter. 2025 Sep 15;38(5):412-419. doi: 10.37201/req/060.2025.
is an aerobic, Gram-positive coryneform bacterium whose clinical relevance has not yet been clearly established. Although an increasing number of isolates have been documented in clinical settings, its role in human pathogenesis remains uncertain and warrants further characterization.
We retrospectively analyzed 116 isolates obtained from symptomatic outpatients in the Rhine-Ruhr metropolitan area (Germany) between January 2021 and February 2023. Clinical and demographic data, specimen types, and co-isolated organisms were recorded. Antimicrobial susceptibility testing (AST) was performed using broth microdilution, and results were interpreted according to EUCAST guidelines.
Most isolates were recovered from urine (58.6%) and wound swabs (30.2%), primarily from older adults. A statistically significant association was found between specimen type and patient sex and age. While was usually detected in polymicrobial cultures (75%), two pure-culture cases were identified: one in urine and one in synovial fluid. AST revealed high susceptibility to beta-lactams and linezolid, with variable response to fluoroquinolones.
is a rare opportunistic pathogen with potential clinical relevance in urogenital and wound infections. Its low pathogenicity suggests it is more likely a secondary colonizer or commensal. Further studies are needed to better understand its clinical significance and impact on human health.
[细菌名称]是一种需氧的革兰氏阳性棒状杆菌,其临床相关性尚未明确确立。尽管临床环境中记录的分离株数量不断增加,但其在人类发病机制中的作用仍不确定,值得进一步表征。
我们回顾性分析了2021年1月至2023年2月期间从德国莱茵-鲁尔大都市地区有症状门诊患者中获得的116株分离株。记录临床和人口统计学数据、标本类型以及共同分离的微生物。使用肉汤微量稀释法进行抗菌药物敏感性测试(AST),并根据欧洲抗菌药物敏感性测试委员会(EUCAST)指南解释结果。
大多数分离株从尿液(58.6%)和伤口拭子(30.2%)中分离得到,主要来自老年人。在标本类型与患者性别和年龄之间发现了统计学上的显著关联。虽然[细菌名称]通常在多种微生物培养物中检测到(75%),但鉴定出两例纯培养病例:一例在尿液中,一例在滑液中。AST显示对β-内酰胺类和利奈唑胺高度敏感,对氟喹诺酮类的反应不一。
[细菌名称]是一种罕见的机会性病原体,在泌尿生殖系统和伤口感染中具有潜在的临床相关性。其低致病性表明它更可能是继发性定植菌或共生菌。需要进一步研究以更好地了解其临床意义及其对人类健康的影响。