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本文引用的文献

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Comorbidities and Risk Factors Associated With Insomnia in the Elderly Population.老年人失眠相关的合并症和危险因素。
J Prim Care Community Health. 2023 Jan-Dec;14:21501319231168721. doi: 10.1177/21501319231168721.
2
Epidemiology of Insomnia: Prevalence, Course, Risk Factors, and Public Health Burden.失眠症的流行病学：患病率、病程、危险因素和公共卫生负担。
Sleep Med Clin. 2022 Jun;17(2):173-191. doi: 10.1016/j.jsmc.2022.03.003. Epub 2022 Apr 23.
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Comorbid Insomnia and Obstructive Sleep Apnea (COMISA): Current Concepts of Patient Management.共病性失眠和阻塞性睡眠呼吸暂停（COMISA）：患者管理的当前概念。
Int J Environ Res Public Health. 2021 Sep 1;18(17):9248. doi: 10.3390/ijerph18179248.
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Alterations of Subcortical Brain Structures in Paradoxical and Psychophysiological Insomnia Disorder.矛盾性失眠和心理生理性失眠障碍患者皮质下脑结构的改变
Front Psychiatry. 2021 May 7;12:661286. doi: 10.3389/fpsyt.2021.661286. eCollection 2021.
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Personality profiles in paradoxical insomnia: a case-control study.矛盾性失眠的人格特征：一项病例对照研究。
Sleep Sci. 2020 Oct-Dec;13(4):242-248. doi: 10.5935/1984-0063.20190148.
6
Paradoxical insomnia and subjective-objective sleep discrepancy: A review.矛盾性失眠和主客观睡眠差异：综述。
Sleep Med Rev. 2018 Aug;40:196-202. doi: 10.1016/j.smrv.2018.01.002. Epub 2018 Jan 6.
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Anxiety and depression in paradoxical insomnia: a case-control study.矛盾性失眠中的焦虑与抑郁：一项病例对照研究。
Neuropsychiatr Dis Treat. 2018 Jan 8;14:231-238. doi: 10.2147/NDT.S156058. eCollection 2018.
8
Obstructive Sleep Apnea without Obesity Is Common and Difficult to Treat: Evidence for a Distinct Pathophysiological Phenotype.无肥胖的阻塞性睡眠呼吸暂停很常见且难以治疗：一种独特病理生理表型的证据
J Clin Sleep Med. 2017 Jan 15;13(1):81-88. doi: 10.5664/jcsm.6394.
9
Subjective-objective sleep discrepancy among older adults: associations with insomnia diagnosis and insomnia treatment.老年人的主观-客观睡眠差异：与失眠诊断和失眠治疗的关联。
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10
Polysomnographic findings in a cohort of chronic insomnia patients with benzodiazepine abuse.苯二氮䓬类药物滥用的慢性失眠患者队列的多导睡眠图结果。
J Clin Sleep Med. 2014 Jan 15;10(1):35-42. doi: 10.5664/jcsm.3354.

矛盾性失眠与非典型阻塞性睡眠呼吸暂停或混合性睡眠障碍？病例报告与文献综述

Paradoxical Insomnia Versus Atypical Obstructive Sleep Apnea or Mixed Disorder? Case Report and Literature Review.

作者信息

Haslam Alden Xavier, Romero Adrián Coulson, Espinoza Torrez Camila Angélica, Ampié Espinoza Manuel

机构信息

Hospital Escuela Alejandro Dávila Bolaños Managua Nicaragua.

Hospital Escuela Manolo Morales Peralta Managua Nicaragua.

出版信息

Clin Case Rep. 2025 Sep 10;13(9):e70883. doi: 10.1002/ccr3.70883. eCollection 2025 Sep.

DOI:10.1002/ccr3.70883
PMID:40948704
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12422947/
Abstract

Paradoxical insomnia remains an underdiagnosed condition due to its subjective nature and diagnostic challenges. Clinicians should suspect it in patients with severe sleep complaints but minimal daytime impairment, particularly those resistant to multiple treatments. Coexisting disorders, such as obstructive sleep apnea, must be considered to ensure an accurate diagnosis and appropriate management.

摘要

反常性失眠因其主观性和诊断挑战，仍然是一种诊断不足的病症。临床医生应对严重睡眠主诉但日间功能损害轻微的患者，尤其是那些对多种治疗有抵抗性的患者怀疑患有此病。必须考虑并存疾病，如阻塞性睡眠呼吸暂停，以确保准确诊断和适当管理。