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Omega-3 polyunsaturated fatty acids in diabetic-associated cognitive dysfunction: a nutritional therapeutic perspective.

作者信息

Cui Chunying, Yang Yan, Liu Pengfei, Gao Yan, Song Daqing, Li Shangbin

机构信息

Emergency Department, Jining No.1 People's Hospital, Jining, Shandong, China.

Department of Geriatric Neurology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.

出版信息

Front Nutr. 2025 Aug 29;12:1651304. doi: 10.3389/fnut.2025.1651304. eCollection 2025.

DOI:10.3389/fnut.2025.1651304
PMID:40948877
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12425726/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b7a/12425726/1c680a5ca96a/fnut-12-1651304-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b7a/12425726/1c680a5ca96a/fnut-12-1651304-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b7a/12425726/1c680a5ca96a/fnut-12-1651304-g0001.jpg

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本文引用的文献

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Impact of Omega-3 on Endocannabinoid System Expression and Function, Enhancing Cognition and Behavior in Male Mice.ω-3对雄性小鼠内源性大麻素系统表达和功能的影响，增强认知和行为能力。
Nutrients. 2024 Dec 17;16(24):4344. doi: 10.3390/nu16244344.
2
Worldwide trends in diabetes prevalence and treatment from 1990 to 2022: a pooled analysis of 1108 population-representative studies with 141 million participants.全球糖尿病患病率和治疗趋势 1990 年至 2022 年：基于 14100 万参与者的 1108 项人群代表性研究的汇总分析。
Lancet. 2024 Nov 23;404(10467):2077-2093. doi: 10.1016/S0140-6736(24)02317-1. Epub 2024 Nov 13.
3
A Mixture of Soybean Oil and Lard Alleviates Postpartum Cognitive Impairment via Regulating the Brain Fatty Acid Composition and SCFA/ERK(1/2)/CREB/BDNF Pathway.
大豆油和猪油的混合物通过调节大脑脂肪酸组成和 SCFA/ERK(1/2)/CREB/BDNF 通路缓解产后认知障碍。
Nutrients. 2024 Aug 10;16(16):2641. doi: 10.3390/nu16162641.
4
Metformin improves cognitive dysfunction through SIRT1/NLRP3 pathway-mediated neuroinflammation in db/db mice.二甲双胍通过 SIRT1/NLRP3 通路介导的神经炎症改善 db/db 小鼠的认知功能障碍。
J Mol Med (Berl). 2024 Sep;102(9):1101-1115. doi: 10.1007/s00109-024-02465-1. Epub 2024 Jul 2.
5
Sleep restriction promotes brain oxidative stress and inflammation, and aggravates cognitive impairment in insulin-resistant mice.睡眠限制可促进大脑氧化应激和炎症反应，并加重胰岛素抵抗小鼠的认知障碍。
Psychoneuroendocrinology. 2024 Aug;166:107065. doi: 10.1016/j.psyneuen.2024.107065. Epub 2024 Apr 29.
6
Eicosapentaenoic acid activates the P62/KEAP1/NRF2 pathway for the prevention of diabetes-associated cognitive dysfunction.二十碳五烯酸通过激活 P62/KEAP1/NRF2 通路预防糖尿病相关认知功能障碍。
Food Funct. 2024 May 20;15(10):5251-5271. doi: 10.1039/d4fo00774c.
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Astaxanthin and DHA Supplementation Modulates the Maternal Undernutrition-induced Impairment of Cognitive Behavior and Synaptic Plasticity in Adult Life of Offspring's -Exploring the Molecular Mechanism.虾青素和二十二碳六烯酸补充剂可调节母体营养不足引起的后代成年期认知行为和突触可塑性损伤——探索分子机制。
Mol Neurobiol. 2024 Nov;61(11):8975-8995. doi: 10.1007/s12035-024-04147-y. Epub 2024 Apr 5.
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Naunyn Schmiedebergs Arch Pharmacol. 2024 Sep;397(9):6563-6575. doi: 10.1007/s00210-024-03028-4. Epub 2024 Mar 9.
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BMC Endocr Disord. 2023 Nov 25;23(1):259. doi: 10.1186/s12902-023-01511-2.
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Ketohexokinase-dependent metabolism of cerebral endogenous fructose in microglia drives diabetes-associated cognitive dysfunction.脑内源性果糖在小胶质细胞中的酮己糖激酶依赖性代谢驱动糖尿病相关认知功能障碍。
Exp Mol Med. 2023 Nov;55(11):2417-2432. doi: 10.1038/s12276-023-01112-y. Epub 2023 Nov 1.