Viala J J, Guyotat D, Vu Van H, Ville D, Gentilhomme O, Bryon P A
Nouv Rev Fr Hematol (1978). 1985;27(6):397-401.
A 21 year-old man and a 17 year-old woman presented with severe anemia of unknown etiology. The bone marrow aspiration showed many erythroblasts which were morphologically normal, but there was no reticulocytosis; the 59Fe kinetics were typical of a major ineffective erythropoiesis. A rapid and total improvement occurred following steroid treatment. In the first case, there was a transient and cortico-responsive thrombocytopenia before and after the anemia and in the second case, the antiglobulin test was sometimes weakly positive. An immunological disturbance against the late erythroblasts is likely. Perhaps these case are not very different from those reported as "hemolytic anemia with reticulocytopenia".
一名21岁男性和一名17岁女性因病因不明的严重贫血前来就诊。骨髓穿刺显示有许多形态正常的成红细胞，但不存在网织红细胞增多；59铁动力学表现为典型的严重无效红细胞生成。类固醇治疗后病情迅速且完全好转。在第一例中，贫血前后出现了短暂的、皮质激素反应性血小板减少，在第二例中，抗球蛋白试验有时呈弱阳性。可能存在针对晚期成红细胞的免疫紊乱。也许这些病例与报道的“伴有网织红细胞减少的溶血性贫血”病例并无太大差异。
