Wang Chenglong, Lei Yang
Spinal Surgery Department, Mianyang Orthopaedic Hospital, Mianyang, Sichuan, China.
Department of Spinal & Bone Tumors (1), The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Front Surg. 2025 Aug 29;12:1555039. doi: 10.3389/fsurg.2025.1555039. eCollection 2025.
Postoperative infections following spinal fusion procedures are commonly caused by pathogens such as , coagulase-negative , species, and . However, cases involving as a causative agent are rarely documented in the literature. We report a case of postoperative infection after anterior cervical spinal fusion surgery. After empirical antimicrobial therapy failed, high-throughput nucleic acid sequencing detected in the patient's cerebrospinal fluid-a rare and previously unreported finding. Upon switching to a more sensitive antibiotic regimen, the patient's symptoms improved significantly. This case highlights an unusual etiology and provides a comprehensive documentation of the treatment process, aiming to assist clinicians in the diagnosis and management of similar infections.
脊柱融合手术后的术后感染通常由凝固酶阴性葡萄球菌等病原体引起。然而，文献中很少记录以[具体病原体名称缺失]作为病原体的病例。我们报告一例颈椎前路融合手术后的术后感染病例。经验性抗菌治疗失败后，高通量核酸测序在患者脑脊液中检测到[具体病原体名称缺失]——这是一个罕见且此前未报告的发现。改用更敏感的抗生素治疗方案后，患者症状明显改善。本病例突出了一种不寻常的病因，并提供了治疗过程的全面记录，旨在帮助临床医生诊断和管理类似感染。
