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低能量长时间消融治疗高阻抗左心室心尖部室性早搏

Low Power Long Duration Ablation for High Impedance Left Ventricular Summit PVCs.

作者信息

Tsukagoshi Yutsuki, Nakamura Keijiro, Kitano Shoma, Sahara Naohiko, Hara Hidehiko

机构信息

Division of Cardiovascular Medicine Toho University Ohashi Medical Center Tokyo Japan.

出版信息

J Arrhythm. 2025 Sep 11;41(5):e70185. doi: 10.1002/joa3.70185. eCollection 2025 Oct.

DOI:10.1002/joa3.70185
PMID:40950383
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12423545/
Abstract

Low-power, long-duration (LPLD) ablation (≤ 25 W for ≥ 60 s with 30 mL/min irrigation) was applied to high-impedance (≥ 150 Ω) left ventricular summit PVC sites via the anterior interventricular vein. Power was escalated stepwise (10 W → 12 W → 15 W → 18 W) under strict safety criteria. Computer simulations demonstrated safe lesion formation at 20 W, whereas 30 W exceeded 100°C, predicting steam-pop risk. This approach achieved 66.7% acute success without complications, highlighting LPLD as a promising option for challenging high-impedance coronary venous ablation sites.

摘要

通过前室间静脉,将低能量、长时间(LPLD)消融(以30毫升/分钟的灌注速度,≤25瓦持续≥60秒)应用于高阻抗(≥150Ω)的左心室心尖室性早搏部位。在严格的安全标准下,功率逐步升高(10瓦→12瓦→15瓦→18瓦)。计算机模拟表明,20瓦时可安全形成损伤,而30瓦时超过100°C,预示有蒸汽泡风险。该方法取得了66.7%的急性成功率且无并发症,突出了LPLD作为具有挑战性的高阻抗冠状静脉消融部位的一种有前景的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a3c/12423545/919a6ac83e69/JOA3-41-e70185-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a3c/12423545/a90e1e20a2ef/JOA3-41-e70185-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a3c/12423545/e7e7f4f84e25/JOA3-41-e70185-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a3c/12423545/919a6ac83e69/JOA3-41-e70185-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a3c/12423545/a90e1e20a2ef/JOA3-41-e70185-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a3c/12423545/e7e7f4f84e25/JOA3-41-e70185-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a3c/12423545/919a6ac83e69/JOA3-41-e70185-g002.jpg

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本文引用的文献

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Med Eng Phys. 2024 Sep;131:104226. doi: 10.1016/j.medengphy.2024.104226. Epub 2024 Aug 21.
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Overcoming High Impedance in the Transitional Area of the Distal Great Cardiac Vein during Radiofrequency Catheter Ablation of Ventricular Arrhythmia.在室性心律失常的射频导管消融术中克服大心静脉远端过渡区的高阻抗
J Cardiovasc Dev Dis. 2022 Aug 12;9(8):264. doi: 10.3390/jcdd9080264.
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Effect of Baseline Impedance in Radiofrequency Delivery on Lesion Characteristics and the Relationship Between Impedance and Steam Pops.
射频消融时基线阻抗对损伤特征的影响以及阻抗与蒸汽泡之间的关系
Front Cardiovasc Med. 2022 Apr 27;9:872961. doi: 10.3389/fcvm.2022.872961. eCollection 2022.
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Computer modeling of radiofrequency cardiac ablation: 30 years of bioengineering research.计算机模拟射频心脏消融术:30 年的生物工程研究。
Comput Methods Programs Biomed. 2022 Feb;214:106546. doi: 10.1016/j.cmpb.2021.106546. Epub 2021 Nov 18.
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Impedance fluctuation and steam pop occurrence during radiofrequency current ablation: An experimental in vitro model.射频电流消融过程中的阻抗波动和蒸汽爆裂发生:一种体外实验模型。
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