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全扁桃体切除术与囊内扁桃体切除术后重度和极重度阻塞性睡眠呼吸暂停的儿科预后

Pediatric Outcomes for Severe and Very Severe Obstructive Sleep Apnea After Total vs. Intracapsular Tonsillectomy.

作者信息

Hurly Jordyn A, Clements Anna Christina, Ryan Marisa A, Ballard Megan, Jenks Carolyn, Tunkel David E, Walsh Jonathan M

机构信息

Johns Hopkins University School of Medicine Baltimore Maryland USA.

Department of Otolaryngology-Head and Neck Surgery University of Washington Seattle WA USA.

出版信息

Laryngoscope Investig Otolaryngol. 2025 Sep 13;10(5):e70255. doi: 10.1002/lio2.70255. eCollection 2025 Oct.

DOI:10.1002/lio2.70255
PMID:40950569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12432330/
Abstract

OBJECTIVES

Intracapsular tonsillectomy is associated with decreased postoperative pain, shortened recovery, and decreased bleeding risk. No study has specifically investigated its use in patients with exclusively severe or very severe obstructive sleep apnea syndrome (OSAS). Our study aimed to report severe OSAS outcomes following intracapsular (IT) compared to total tonsillectomy (TT) in pediatric patients with severe and very severe OSAS.

METHODS

We conducted a retrospective study including patients ≤ 18 years of age who underwent adenotonsillectomy or tonsillectomy between June 2018 and June 2022 at a tertiary care center. Patients were categorized preoperatively as having severe OSAS (OAHI ≥ 10) or very severe OSAS (OAHI ≥ 30). Primary outcomes included obstructive apnea-hypopnea index (OAHI), oxygen saturation nadir, presence of hypercarbia, and respiratory disturbance index (RDI) as measured on postoperative polysomnography, as well as residual OSAS requiring CPAP.

RESULTS

Of 57 patients in this study, the mean age was 4.5 (±2.9) and 59.7% were male. There was no significant difference in postoperative residual OSAS outcomes following surgery for patients in either severity group, with a mean time to follow up polysomnogram of 237 (range: 24-885) days.

CONCLUSION

Our study reveals that for both severe OSAS and very severe OSAS, there is no difference in the primary outcome of postoperative OAHI with regard to surgical technique; however, long-term postoperative outcomes are still needed.

LEVEL OF EVIDENCE

摘要

目的

囊内扁桃体切除术与术后疼痛减轻、恢复时间缩短和出血风险降低相关。尚无研究专门调查其在单纯重度或极重度阻塞性睡眠呼吸暂停综合征(OSAS)患者中的应用。我们的研究旨在报告在患有重度和极重度OSAS的儿科患者中,与全扁桃体切除术(TT)相比,囊内扁桃体切除术(IT)后的重度OSAS结局。

方法

我们进行了一项回顾性研究,纳入了2018年6月至2022年6月在一家三级医疗中心接受腺样体扁桃体切除术或扁桃体切除术的18岁及以下患者。术前将患者分类为患有重度OSAS(阻塞性呼吸暂停低通气指数[OAHI]≥10)或极重度OSAS(OAHI≥30)。主要结局包括术后多导睡眠图测量的阻塞性呼吸暂停低通气指数(OAHI)、最低氧饱和度、高碳酸血症的存在以及呼吸紊乱指数(RDI),以及需要持续气道正压通气(CPAP)的残余OSAS。

结果

本研究中的57例患者,平均年龄为4.5(±2.9)岁,59.7%为男性。两个严重程度组的患者术后残余OSAS结局无显著差异,随访多导睡眠图的平均时间为237天(范围:24 - 885天)。

结论

我们的研究表明,对于重度OSAS和极重度OSAS,手术技术在术后OAHI主要结局方面没有差异;然而,仍需要长期术后结局。

证据级别

4级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46f7/12432330/c2a4fc95f542/LIO2-10-e70255-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46f7/12432330/1f34abfb9a5c/LIO2-10-e70255-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46f7/12432330/c2a4fc95f542/LIO2-10-e70255-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46f7/12432330/1f34abfb9a5c/LIO2-10-e70255-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46f7/12432330/c2a4fc95f542/LIO2-10-e70255-g001.jpg

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本文引用的文献

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Eur Arch Otorhinolaryngol. 2022 Jun;279(6):3089-3093. doi: 10.1007/s00405-021-07119-3. Epub 2021 Oct 10.
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Intracapsular coblation tonsillectomy versus extracapsular coblation tonsillectomy: a systematic review and a meta-analysis.经黏膜下切除术与经黏膜外切除术治疗扁桃体的比较:系统评价和荟萃分析。
Eur Arch Otorhinolaryngol. 2021 Mar;278(3):637-644. doi: 10.1007/s00405-020-06178-2. Epub 2020 Jul 4.
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Ambulatory tonsillectomy for children with severe obstructive sleep apnea without risk factors.
儿童伴或不伴危险因素的阻塞性睡眠呼吸暂停行门诊扁桃体切除术。
Am J Otolaryngol. 2020 Jul-Aug;41(4):102467. doi: 10.1016/j.amjoto.2020.102467. Epub 2020 Mar 20.
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Targeting the gut microbiota to influence brain development and function in early life.靶向肠道微生物群以影响生命早期的大脑发育和功能。
Neurosci Biobehav Rev. 2018 Dec;95:191-201. doi: 10.1016/j.neubiorev.2018.09.002. Epub 2018 Sep 6.
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Postoperative Monitoring Following Adenotonsillectomy for Severe Obstructive Sleep Apnea.重度阻塞性睡眠呼吸暂停患者行腺样体扁桃体切除术后的监测
Ann Otol Rhinol Laryngol. 2018 Nov;127(11):783-790. doi: 10.1177/0003489418794700. Epub 2018 Sep 5.
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Comparative Effectiveness of Partial versus Total Tonsillectomy in Children.儿童部分扁桃体切除术与全扁桃体切除术的比较疗效
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Risk of reoperation after tonsillotomy versus tonsillectomy: a population-based cohort study.扁桃体切开术与扁桃体切除术后再次手术的风险:一项基于人群的队列研究。
Eur Arch Otorhinolaryngol. 2016 Oct;273(10):3263-8. doi: 10.1007/s00405-015-3871-7. Epub 2016 Jan 4.
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