Freiria de Oliveira Carolina Alves, Macedo Ana Paula, Oliveira Viviane de Cássia, de Moraes Leonardo Guedes Silva, Tonin Bruna Santos Honório, Galo Rodrigo, Pagnano Valéria Oliveira
Int J Prosthodont. 2025 Sep 16;0(0):1-21. doi: 10.11607/ijp.9470.
This in vitro study evaluated the effects of peracetic acid (PA, 0.25 mg/mL) and cetylpyridinium chloride (CPC, 0.5 mg/mL) solutions on the surfaces of heat-polymerized acrylic resin and cobalt-chromium alloy (Co-Cr).
Heat-7 polymerized acrylic resin specimens, 90 (ᴓ1_4 × 3 m_m),_ 7_0 (65 × 10 × 3.3 mm), and 78 Co-Cr (ᴓ1_2 × 3 m_m) underwent daily 10-minute immersions for periods simulating roughly 3 years (8-23 days) or 5 years (13-38 days) in: distilled water (8/13 days), CPC 10 (23/38 days), or PA (8/13 days). Evaluated parameters for acrylic resin included: surface 11 r_o_u_g_h_n_e_s_s (R_a, μm),_ Knoop Hardness (HK, kgf/mm²), c_o_l_o_r c_h_a_n_g_e (ΔE),_ a_n_d f_l_e_x_u_r_a_l strength (MPa). For Co-Cr, were assessed: Ra, gloss change (ΔGU), and chemical degradation and surface topography using a scanning electron microscope (SEM). Data were analyzed by ANOVA, Wald Test, and Kruskal-W_a_l_l_i_s f_o_l_l_o_w_e_d b_y D_u_n_n's t_e_s_t _(_α = _0.05).
PA enhanced resin flexural strength. CPC induced minor resin discoloration post 3 years (p=0.015). For Co-Cr, after 5 years, roughness values rose significantly in both CPC and PA immersions, PA also enhanced corrosion resistance through the formation of a more stable passivation layer.
PA proved promising as a disinfectant for removable partial denture, suggesting a new clinical application due to its high oxidative potential. PA prosthesis disinfection in laboratories is recommended, considering positive impact on preserving mechanical properties and preventing metal alloy corrosion.
本体外研究评估了过氧乙酸（PA，0.25毫克/毫升）和西吡氯铵（CPC，0.5毫克/毫升）溶液对热聚合丙烯酸树脂和钴铬合金（Co-Cr）表面的影响。
热聚合丙烯酸树脂试件，90个（直径14×3毫米），70个（65×10×3.3毫米），以及78个Co-Cr（直径12×3毫米），每天浸泡10分钟，浸泡时间模拟大约3年（8 - 23天）或5年（13 - 38天），浸泡于：蒸馏水（8/13天）、CPC 10（23/38天）或PA（8/13天）。评估丙烯酸树脂的参数包括：表面粗糙度（Ra，微米）、努氏硬度（HK，千克力/平方毫米）、颜色变化（ΔE）以及挠曲强度（兆帕）。对于Co-Cr，评估参数包括：Ra、光泽度变化（ΔGU），以及使用扫描电子显微镜（SEM）观察化学降解和表面形貌。数据通过方差分析、 Wald检验以及Kruskal-Wallis检验后进行Dunns检验（α = 0.05）分析。
PA提高了树脂的挠曲强度。3年后，CPC导致树脂轻微变色（p = 0.015）。对于Co-Cr，5年后，在CPC和PA浸泡中粗糙度值均显著升高，PA还通过形成更稳定的钝化层提高了耐腐蚀性。
PA被证明有望作为可摘局部义齿的消毒剂，因其高氧化电位而提示了一种新的临床应用。考虑到对保留机械性能和防止金属合金腐蚀的积极影响，建议在实验室中对PA进行义齿消毒。
