Klümper Uli, Fang Peiju, Li Bing, Xia Yu, Frigon Dominic, Hamilton Kerry A, Quon Hunter, Berendonk Thomas U, de la Cruz Barron Magali
Technische Universität Dresden, Institute of Hydrobiology, Dresden, Germany.
Tsinghua University, Tsinghua Shenzhen International Graduate School, Institute of Environment and Ecology, Shenzhen, China.
NPJ Antimicrob Resist. 2025 Sep 16;3(1):81. doi: 10.1038/s44259-025-00154-8.
Antibiotic resistance gene (ARG) mobility plays a crucial role in the spread of antimicrobial resistance across One Health settings. Current environmental surveillance often overlooks the significance of ARG mobility, limiting risk assessment accuracy. This perspective highlights that with recent methodological advances in detecting ARG mobility, relevant databases, and improved quantitative microbial risk assessment frameworks, the time to integrate ARG mobility into environmental antimicrobial resistance (AMR) surveillance and risk assessment is now.
抗生素抗性基因（ARG）的移动性在“同一健康”背景下抗菌药物耐药性的传播中起着关键作用。当前的环境监测常常忽视ARG移动性的重要性，从而限制了风险评估的准确性。这一观点强调，随着近期在检测ARG移动性方面的方法学进展、相关数据库的建立以及定量微生物风险评估框架的改进，现在是将ARG移动性纳入环境抗菌药物耐药性（AMR）监测和风险评估的时候了。
