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恒河猴中血型B特异性三糖的生物合成

Biosynthesis of the blood-group-B-specific trisaccharide in a rhesus monkey.

作者信息

Chester M A, Hallgren P, Lindberg B S, Lundblad A

出版信息

Eur J Biochem. 1977 Jul 1;77(1):87-91. doi: 10.1111/j.1432-1033.1977.tb11644.x.

Abstract

A Rhesus monkey, serologically grouped as B, has been shown to excrete low-molecular-weight carbohydrate material in urine closely related to that found in human urine. Galactose feeding resulted in the excretion of a trisaccharide which was shown to be identical to the trisaccharide isolated from the urine of group B humans under the same conditions. Experiments in which [14C]galactose was administered both orally and via an intestinal vein demonstrated that the intestine is the site of biosynthesis.

摘要

一只血清学分类为B型的恒河猴已被证明会在尿液中排泄与人类尿液中发现的低分子量碳水化合物物质密切相关的物质。喂食半乳糖导致一种三糖的排泄,经证明该三糖与在相同条件下从B型血人类尿液中分离出的三糖相同。口服和经肠静脉给予[14C]半乳糖的实验表明,肠道是生物合成的场所。

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