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维生素在控制肥胖/肥胖症方面的治疗作用及机制——近期研究概述

Therapeutic role and mechanisms of vitamins for controlling obesity/adiposity-a brief overview of recent studies.

作者信息

Rahman Md Hasinur, Mondal Md Ibrahim H

机构信息

Polymer and Textile Research Lab, Department of Applied Chemistry and Chemical Engineering, Rajshahi University, Rajshahi, Bangladesh.

出版信息

Int J Obes (Lond). 2025 Sep 18. doi: 10.1038/s41366-025-01908-0.

Abstract

Obesity/adiposity, an often-intractable disease with serious physical, economic, and societal consequences, is a major problem for health practitioners. Despite extensive research, obesity remains a kind of pandemic. There is significant evidence that individuals with obesity react to both fat-soluble and water-soluble vitamin levels in their serum. Vitamins correlate negatively with body weight, body mass index, and body composition. Certain vitamins may possess anti-adipogenic, anti-inflammatory, and antioxidant properties. Yet still, there is no consensus among researchers about the general impact of vitamins on obesity. A clearer understanding of the effects of vitamins on obesity will make dietary interventions more effective in preventing and treating obesity and its complications. This article analyses the current data about the impact of vitamins on controlling obesity, including their role, action mechanisms and obesity-related metabolic statuses. Such an analysis could enhance our understanding of the effects of vitamins on obesity. So, this article could assist future researchers who are working toward better protocols for treating obesity.

摘要

肥胖症/肥胖,这一常难以治疗且会引发严重身体、经济和社会后果的疾病,是健康从业者面临的重大问题。尽管进行了广泛研究,但肥胖症仍然是一种流行病。有大量证据表明,肥胖个体对其血清中脂溶性和水溶性维生素水平均有反应。维生素与体重、体重指数和身体成分呈负相关。某些维生素可能具有抗脂肪生成、抗炎和抗氧化特性。然而,研究人员对于维生素对肥胖症的总体影响仍未达成共识。更清楚地了解维生素对肥胖症的影响将使饮食干预在预防和治疗肥胖症及其并发症方面更有效。本文分析了有关维生素对控制肥胖症影响的现有数据,包括它们的作用、作用机制以及与肥胖相关的代谢状态。这样的分析可以增进我们对维生素对肥胖症影响的理解。因此,本文可以帮助未来致力于制定更好的肥胖症治疗方案的研究人员。

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