补充维生素D对人体测量指标有积极影响：来自一项汇总荟萃分析的证据。

Vitamin D supplementation positively affects anthropometric indices: Evidence obtained from an umbrella meta-analysis.

作者信息

Musazadeh Vali, Zarezadeh Meysam, Ghalichi Faezeh, Kalajahi Fateme Hamedi, Ghoreishi Zohreh

机构信息

Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.

Department of Community Nutrition, School of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Front Nutr. 2022 Sep 7;9:980749. doi: 10.3389/fnut.2022.980749. eCollection 2022.

Despite the growing evidence from meta-analyses on vitamin D's anti-obesity properties, their results are controversial. The current umbrella review was performed to assess the available evidence and provide a conclusive explanation in this regard. The international databases PubMed, Scopus, Embase, Web of Science and Google Scholar were systematically searched till March, 2022. A random-effects model was used to run the meta-analysis. All meta-analyses that examined the effect of vitamin D supplementation on BW, BMI, WC, and fat mass were included. Findings of 14 meta-analyses revealed that vitamin D supplementation reduced body mass index (BMI) (ES: -0.11 kg/m; 95% CI: -0.18, -0.05, ?0.001; = 61.0%, < 0.001), and waist circumference (WC) (ES = -0.79 cm; 95% CI: -1.20, -0.37; < 0.001; = 46.5%, = 0.096) in comparison to control group. However, the effects of vitamin D on body weight (ES = -0.16 kg, 95% CI: -0.36, 0.04; = 0.125; = 57.0%, = 0.017), and fat mass (ES: 0.02, 95% CI: -0.20, 0.24, = 0.868; = 0.0%, = 0.531) were not considerable. Vitamin D supplementation significantly improved levels of obesity indices such as BMI, and WC.

尽管来自荟萃分析的关于维生素D抗肥胖特性的证据越来越多，但其结果仍存在争议。进行当前的综合评价是为了评估现有证据并在这方面提供确凿的解释。对国际数据库PubMed、Scopus、Embase、科学网和谷歌学术进行了系统检索，直至2022年3月。使用随机效应模型进行荟萃分析。纳入了所有研究维生素D补充剂对体重、体重指数、腰围和脂肪量影响的荟萃分析。14项荟萃分析的结果显示，与对照组相比，补充维生素D可降低体重指数（ES：-0.11kg/m²；95%CI：-0.18，-0.05，P<0.001；I²=61.0%）和腰围（WC）（ES=-0.79cm；95%CI：-1.20，-0.37；P<0.001；I²=46.5%，P=0.096）。然而，维生素D对体重（ES=-0.16kg，95%CI：-0.36，0.04；P=0.125；I²=57.0%，P=0.017）和脂肪量（ES：0.02，95%CI：-0.20，0.24，P=0.868；I²=0.0%，P=0.531）的影响并不显著。补充维生素D可显著改善体重指数和腰围等肥胖指标水平。