Zhou C N, Yang W Z, Ding Z X, Wang Y X, Shen H, Fan X J, Ha X W
Adv Exp Med Biol. 1985;193:111-5. doi: 10.1007/978-1-4613-2165-1_13.
In the present study it has been demonstrated that the ultrastructural changes in mouse ear skin after PDT action occurred much more distinct and earlier than those observed in the histological study. Various types of cells in the skin respond to the photodynamic action differently. The endothelial cells, fibroblasts and nerve fibers are most sensitive. In contrast, the keratinocytes and chondrocytes often remain rather well preserved after PDT treatment. The possible mechanism of PDT action was briefly discussed.
在本研究中已证明，光动力疗法（PDT）作用后小鼠耳部皮肤的超微结构变化比组织学研究中观察到的变化更为明显且更早出现。皮肤中的各种细胞对光动力作用的反应不同。内皮细胞、成纤维细胞和神经纤维最为敏感。相比之下，角质形成细胞和软骨细胞在PDT治疗后通常保存得相当完好。简要讨论了PDT作用的可能机制。
