Petzke Tara M, Köteles Ferenc, Van den Bergh Omer, Witthöft Michael
Biopsychosoc Sci Med. 2025 Oct 1;87(8):565-575. doi: 10.1097/PSY.0000000000001425. Epub 2025 Aug 7.
According to recent empirical taxonomies (eg, the Hierarchical Taxonomy of Psychopathology), somatic symptom distress represents a transdiagnostically relevant dimension of psychopathology. To better understand the mechanisms, somatic symptoms can be experimentally provoked by inducing negative affect (in the Affect and Symptom Paradigm, ASP, formerly known as the Affective Picture Paradigm). Potential moderators of this relation include cardiorespiratory activation and body-focused attention.
In this preregistered, cross-sectional study ( https://osf.io/sc57z/ ), we tested whether cardiorespiratory activation and body-focused attention modulate somatic symptoms in the ASP. Participants ( ) completed 3 ASPs, interlaced with cardiorespiratory activation (cycling) and rest. Participants were randomized to a body-attention or distraction condition. We measured heart rate, respiratory rate, and end-tidal CO 2 during these tasks. The data were analyzed using AN(C)OVAs, t tests, and multilevel models.
Exercise significantly increased, and rest significantly decreased immediatesomatic symptoms ( ). High levels of somatic symptoms were significantly related to a sustained greater decrease in somatic symptoms in the ASP after cycling (vs. rest, . No significant effect of the attention manipulation was observed ( ).
Rest and exercise temporarily modulate somatic symptom reports, and people with higher baseline somatic symptoms show the strongest beneficial effect of physical activity on symptom reports in the ASP. The findings are compatible with recent models of predictive processing and active inference.
根据最近的实证分类法（例如，精神病理学层次分类法），躯体症状困扰代表了精神病理学中一个跨诊断相关的维度。为了更好地理解其机制，可以通过诱发负面情绪（在情绪与症状范式，ASP，以前称为情感图片范式）来实验性地引发躯体症状。这种关系的潜在调节因素包括心肺激活和专注于身体的注意力。
在这项预先注册的横断面研究（https://osf.io/sc57z/）中，我们测试了心肺激活和专注于身体的注意力是否会调节ASP中的躯体症状。参与者（ ）完成了3次ASP，期间穿插心肺激活（骑自行车）和休息。参与者被随机分配到专注于身体或分散注意力的条件下。我们在这些任务中测量了心率、呼吸频率和呼气末二氧化碳。数据使用方差分析（AN(C)OVA）、t检验和多层次模型进行分析。
运动显著增加，而休息显著减少即时躯体症状（ ）。高水平的躯体症状与骑自行车后（与休息相比， ）ASP中躯体症状持续更大程度的减少显著相关。未观察到注意力操纵的显著影响（ ）。
休息和运动暂时调节躯体症状报告，并且基线躯体症状较高的人在ASP中显示出身体活动对症状报告的最强有益效果。这些发现与最近的预测处理和主动推理模型一致。
