Fujii Yukiko, Harada Kouji H
Department of Pharmaceutical Sciences, Daiichi University of Pharmacy.
Laboratory of Food Hygiene and Environmental Health, Kyoto Prefectural University.
Environ Health Prev Med. 2025;30:73. doi: 10.1265/ehpm.25-00002.
Per- and polyfluoroalkyl substances (PFAS) have recently been shown to affect human health at low levels in the blood, according to epidemiological evidence. Consequently, human exposure to these chemicals should be strictly controlled to prevent health risks. This review reports on the potential sources of PFAS using Japan as an example. Tap water has attracted attention as a source of exposure to PFAS. PFAS have also been detected in the air, in household dust, and in consumer products. Furthermore, in the general population, diet is the most common source of exposure, and there is particular concern about human exposure to PFAS accumulated in seafood. Continuous monitoring is important for appropriate management of exposure for both humans and the environment.
根据流行病学证据，全氟和多氟烷基物质（PFAS）最近被证明会在血液中低水平时影响人体健康。因此，应严格控制人类接触这些化学物质以预防健康风险。本综述以日本为例报告了PFAS的潜在来源。自来水作为PFAS的一个接触源已受到关注。在空气、家庭灰尘和消费品中也检测到了PFAS。此外，在普通人群中，饮食是最常见的接触源，人们尤其担心人类接触海鲜中积累的PFAS。持续监测对于人类和环境接触的适当管理很重要。
