Wakui Nobuyuki, Koakutsu Yuna, Watanabe Mai, Yokoyama Yui, Okami Aika, Shirozu Shunsuke, Okada Kotaro, Onuki Yoshinori, Machida Yoshiaki
Division of Applied Pharmaceutical Education and Research, Faculty of Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo , 142-8501, Japan.
Laboratory of Pharmaceutical Technology, School of Pharmacy and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama City, Toyama Prefecture, 930-0194, Japan.
J Cancer Educ. 2025 Sep 18. doi: 10.1007/s13187-025-02733-9.
Although Japan resumed proactive HPV vaccination in 2022 and introduced catch-up initiatives, vaccination rates remain low, partly due to insufficient cancer education during school years. Moreover, male vaccination remains underrecognized despite its cancer prevention benefits. This study evaluated the effect of a planned educational intervention on HPV-related knowledge, willingness to receive vaccination, and recommendation intent among unvaccinated male and female university students. A total of 285 unvaccinated students participated in a planned educational intervention between October 29 and November 3, 2023. As part of a planned educational intervention conducted in a university setting, participants watched an educational YouTube video on HPV and cervical cancer and completed pre- and post-intervention surveys assessing their knowledge, vaccination willingness, and recommendation intent. Data were analyzed using McNemar's test and stepwise multiple regression analysis. Participants' knowledge about HPV and the vaccine significantly improved after the intervention (P < 0.001). Willingness to receive vaccination increased in both male and female participants, with a greater change observed among males (β = 0.79, P < 0.001). Improved knowledge was significantly associated with increased willingness to receive vaccination (β = 0.09, P = 0.001) and recommendation intent (β = 0.05, P = 0.038). These findings demonstrate that a brief, planned educational intervention can enhance vaccine-related knowledge and positively influence attitudes. Future efforts should incorporate such approaches across educational settings, including universities and earlier stages, to strengthen HPV vaccination awareness among both males and females and advance cancer-prevention education.
尽管日本于2022年恢复了积极的人乳头瘤病毒（HPV）疫苗接种并推出了补种计划，但接种率仍然很低，部分原因是在校期间癌症教育不足。此外，尽管男性接种疫苗对预防癌症有益，但仍未得到足够重视。本研究评估了一项有计划的教育干预措施对未接种疫苗的男女大学生的HPV相关知识、接种意愿和推荐意愿的影响。共有285名未接种疫苗的学生参加了2023年10月29日至11月3日的有计划的教育干预。作为在大学环境中进行的有计划的教育干预的一部分，参与者观看了一段关于HPV和宫颈癌的教育性YouTube视频，并完成了干预前后的调查，以评估他们的知识、接种意愿和推荐意愿。数据采用McNemar检验和逐步多元回归分析进行分析。干预后，参与者对HPV和疫苗的知识有了显著提高（P < 0.001）。男性和女性参与者的接种意愿均有所增加，男性的变化更大（β = 0.79，P < 0.001）。知识的提高与接种意愿的增加（β = 0.09，P = 0.001）和推荐意愿的增加（β = 0.05，P = 0.038）显著相关。这些发现表明，一次简短的、有计划的教育干预可以增强与疫苗相关的知识，并对态度产生积极影响。未来的努力应将此类方法纳入包括大学及更早阶段在内的各种教育环境中，以加强男性和女性对HPV疫苗接种的认识，并推进癌症预防教育。
