Tripathi Sonali, Mandrah Vineet, Upadhyay Ritesh, Patel Ashwini Kumar
Department of Anaesthesiology, Chhindwara Institute of Medical Sciences, Chhindwara, Madhya Pradesh, India.
Department of General Surgery, Chhindwara Institute of Medical Sciences, Chhindwara, Madhya Pradesh, India.
Bioinformation. 2025 Jun 30;21(6):1577-1580. doi: 10.6026/973206300211577. eCollection 2025.
Effect of ropivacaine with and without intrathecal fentanyl for spinal anesthesia among patients with scorpion bite is of interest. Patients in the fentanyl-ropivacaine combination group had faster onset of sensory blockade (5.2±1.1 versus 7.8±1.3 minutes, p<0.001) and significantly longer analgesia duration (290±15 versus 180±12 minutes, p<0.001) than patients in the ropivacaine-alone group. Hemodynamic stability and the incidence of adverse effects were similar between the two groups. These results indicate that intrathecal fentanyl enhances the efficacy of ropivacaine in this distinct patient population without compromising safety.
在被蝎子蜇伤的患者中，鞘内注射芬太尼与不注射芬太尼的罗哌卡因用于脊髓麻醉的效果令人关注。与单纯罗哌卡因组患者相比，芬太尼 - 罗哌卡因联合组患者的感觉阻滞起效更快（5.2±1.1分钟对7.8±1.3分钟，p<0.001），镇痛持续时间显著更长（290±15分钟对180±12分钟，p<0.001）。两组之间的血流动力学稳定性和不良反应发生率相似。这些结果表明，在这一特殊患者群体中，鞘内注射芬太尼可增强罗哌卡因的疗效且不影响安全性。
