Pinto Tatiane Nobre, Costa Gisela Lara da, Costa Michael Anderson Teneu, Lima Érica Vitória Dos Santos, Carvalho Tayná Rafaelle Coêlho de, Santos Jadielson da Silva, Silva Kelly Maria Rêgo da, Freire Simone Mousinho, Oliveira Manoel Marques Evangelista
Laboratório de Taxonomia, Bioquímica e Bioprospecção de Fungos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Laboratório de Zoologia e Biologia Parasitária, Universidade Estadual do Piauí, Teresina, Brazil.
New Microbes New Infect. 2025 Sep 3;67:101628. doi: 10.1016/j.nmni.2025.101628. eCollection 2025 Oct.
Bats in Brazil play a crucial ecological role; additionally, these mammals are known hosts of potential zoonotic pathogens and pathogenic fungi. The increase in their interactions with humans and other animals, caused by anthropogenic pressure, can lead to the dispersal of pathogens. Despite this, the fungal microbiome of these animals in Brazil has been little investigated. This project aims to analyze the fungal microbiota of bats and identify potentially pathogenic yeasts in populations of the Cerrado and Caatinga. The study included 47 bats captured in Piauí, Brazil. Samples were collected from the oral mucosa and the isolated yeasts were identified by a polyphasic taxonomy approach, using techniques such as partial sequencing of genes from the ITS region and MALDI-TOF MS. It was possible to isolate 17 yeast samples, including the pathogenic yeasts , ). The importance of continuous surveillance of the fungal microbiota of bats is highlighted, especially in ecologically sensitive areas such as the Cerrado and Caatinga. Detailed characterization of the oral microbiota of these animals contributes to the understanding of ecological interactions with fungi and provides essential data for strategies to prevent zoonoses and protect human and animal health.
巴西的蝙蝠发挥着至关重要的生态作用；此外，这些哺乳动物是潜在人畜共患病原体和致病真菌的已知宿主。人为压力导致它们与人类及其他动物的互动增加，这可能会导致病原体的传播。尽管如此，巴西这些动物的真菌微生物群却鲜有研究。本项目旨在分析蝙蝠的真菌微生物群，并在塞拉多和卡廷加地区的种群中鉴定潜在的致病酵母。该研究纳入了在巴西皮奥伊捕获的47只蝙蝠。从口腔黏膜采集样本，并采用多相分类法，利用ITS区域基因部分测序和基质辅助激光解吸电离飞行时间质谱等技术对分离出的酵母进行鉴定。共分离出17个酵母样本，包括致病酵母 ， 。强调了持续监测蝙蝠真菌微生物群的重要性，尤其是在塞拉多和卡廷加等生态敏感地区。对这些动物口腔微生物群的详细表征有助于理解与真菌的生态相互作用，并为预防人畜共患病和保护人类及动物健康的策略提供重要数据。
