Bloch W W, Austin J C, Cleaton-Jones P E, Wilton-Cox H, Fatti L P
J Oral Pathol. 1977 Sep;6(5):278-87. doi: 10.1111/j.1600-0714.1977.tb01650.x.
A new visible light-cured composite resin, Fotofil, has been developed for the esthetic restoration of anterior teeth. The pulpal responses elicited by this material in unlined cavities and cavities lined with Dycal were compared with those elicited by a negative control consisting of modified zinc oxide-eugenol cement Notebec and a silicate cement Syntrex. The pulpal responses were evaluated in the permanent maxillary and mandibular incisors in vervet monkeys using labial Claterial in each monkey. Groups of 10 monkeys were killed at intervals of 2 days, and 2 and 8 weeks after restoration of the teeth. The most severe pulpal responses were elicited by the unlined Fotofil and Syntrex restorations at all three time intervals. The Dycal lined Fotofil restorations elicited a milder pulp response than the Nobetec at 2 days and 2 weeks. No pulpal response was elicited by the latter two materials at 8 weeks. These results clearly showed that Fotofil and Syntrex are irritant to the dental pulp up to 8 weeks. The placement of a Dycal liner beneath Fotofil restorations reduced the pulpal irritation elicited by this material to levels which were lower than those elicited by the Nobetec control at 2 days and 2 weeks.
一种新型可见光固化复合树脂Fotofil已被研发用于前牙的美学修复。将这种材料在未衬里窝洞和用Dycal衬里的窝洞中引发的牙髓反应，与由改性氧化锌丁香酚水门汀Notebec和硅粘固粉Syntrex组成的阴性对照引发的牙髓反应进行比较。使用每只猴子的唇侧材料，在黑长尾猴的上颌和下颌恒切牙中评估牙髓反应。每组10只猴子在牙齿修复后2天、2周和8周的时间间隔处死。在所有三个时间间隔，未衬里的Fotofil和Syntrex修复体引发的牙髓反应最为严重。在2天和2周时，用Dycal衬里的Fotofil修复体引发的牙髓反应比Nobetec轻。后两种材料在8周时未引发牙髓反应。这些结果清楚地表明，Fotofil和Syntrex在8周内对牙髓有刺激性。在Fotofil修复体下方放置Dycal衬层，可将这种材料引发的牙髓刺激降低到低于Nobetec对照在2天和2周时引发的水平。
