Bloch W W, Cleaton-Jones P E, Austin J C, Pain E
J Oral Pathol. 1981 Apr;10(2):95-100. doi: 10.1111/j.1600-0714.1981.tb01254.x.
The investigation was undertaken to determine the response to Nobetec, a modified zinc oxide-eugenol cement, widely used as a negative control material in pulpal studies, under conditions of high- and low-speed cavity preparation, with and without a cavity liner Dycal. The pulpal responses were evaluated at intervals of 2 days, 2 weeks and 8 weeks in the permanent maxillary and mandibular incisors in 26 vervet monkeys using labial Class V cavities prepared in 208 teeth. Nobetec was found to be more irritant to the dental pulp than Dycal although this difference was not statistically significant and the degree of irritation was low. The pulpal irritation caused by high- and low-speed cavity preparation was similar and choice of speed should be a matter of personal preference.
本研究旨在确定诺贝泰克（Nobetec）的反应，诺贝泰克是一种改性氧化锌丁香酚水门汀，在牙髓研究中广泛用作阴性对照材料，研究在高速和低速窝洞制备条件下，使用和不使用Dycal护髓剂时的情况。在26只黑长尾猴的恒上颌和下颌切牙中，使用208颗牙齿制备唇侧V类洞，分别在2天、2周和8周的时间间隔评估牙髓反应。结果发现，诺贝泰克对牙髓的刺激性比Dycal更大，尽管这种差异没有统计学意义，且刺激程度较低。高速和低速窝洞制备引起的牙髓刺激相似，速度的选择应根据个人偏好。
