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土耳其曲霉病综述:作为家禽中的主要真菌病

A Review on Aspergillosis in Turkey: As a Main Fungal Disease in Poultry.

作者信息

Alhassani Ansam Naji Aboud, Ahmed Abdulrahman T, Sanghvi Gaurav, Ganesan Subbulakshmi, Al-Hetty Hussein Riyadh Abdul Kareem, Sapaev I B, Singh Abhayveer, Sudan Puneet, Mustafa Yasser Fakri, Gholami-Ahangaran Majid

机构信息

Pharmacology and Toxicology Department, Al kitab University, College of Pharmacy, Iraq.

College of Nursing, University of Al Maarif, Al Anbar, Iraq.

出版信息

Vet Med Sci. 2025 Nov;11(6):e70605. doi: 10.1002/vms3.70605.

DOI:10.1002/vms3.70605
PMID:40988581
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12457859/
Abstract

BACKGROUND

Aspergillosis, a fungal disease caused by various species of the genus Aspergillus, poses a significant threat to the health and productivity of turkeys.

OBJECTIVE

The current review aims to synthesize current knowledge regarding the aetiology, pathogenesis, clinical manifestations, diagnostic methods and management strategies associated with aspergillosis in turkeys.

METHODS

A simple narrative literature review was conducted in Google Scholar, PubMed and ScienceDirect databases to identify relevant studies published in peer-reviewed journals. The review focused on the pathogenesis of aspergillosis in turkeys, clinical manifestations, diagnostic techniques and therapeutic strategies.

RESULTS

Aspergillosis typically results from environmental exposure to spores, particularly in settings with poor ventilation and high temperature and humidity, leading to respiratory distress and systemic disease. Clinical signs can vary widely, ranging from mild respiratory symptoms to severe systemic illness, which complicates diagnosis due to overlap with other respiratory diseases. Diagnostic approaches include clinical evaluation, necropsy findings and laboratory tests such as fungal culture and molecular techniques. Effective management requires a multifaceted strategy that encompasses improved biosecurity measures, environmental control and appropriate treatment protocols.

CONCLUSION

Understanding the epidemiology and impact of aspergillosis is crucial for developing effective preventive strategies and mitigating its economic consequences in turkey production. This review underscores the need for continued research to enhance diagnostic capabilities and therapeutic options, ultimately contributing to better health outcomes in turkey populations.

摘要

背景

曲霉菌病是一种由曲霉菌属的多种真菌引起的疾病,对火鸡的健康和生产性能构成重大威胁。

目的

本综述旨在综合目前关于火鸡曲霉菌病的病因、发病机制、临床表现、诊断方法及管理策略的相关知识。

方法

在谷歌学术、PubMed和ScienceDirect数据库中进行了一项简单的叙述性文献综述,以识别发表在同行评审期刊上的相关研究。该综述聚焦于火鸡曲霉菌病的发病机制、临床表现、诊断技术及治疗策略。

结果

曲霉菌病通常是由于环境中接触孢子所致,尤其是在通风不良、温度和湿度较高的环境中,可导致呼吸窘迫和全身性疾病。临床症状差异很大,从轻微的呼吸道症状到严重的全身性疾病不等,由于与其他呼吸道疾病症状重叠,这使得诊断变得复杂。诊断方法包括临床评估、尸检结果以及实验室检测,如真菌培养和分子技术。有效的管理需要多方面的策略,包括改善生物安全措施、环境控制和适当的治疗方案。

结论

了解曲霉菌病的流行病学和影响对于制定有效的预防策略以及减轻其在火鸡生产中的经济后果至关重要。本综述强调需要持续开展研究以提高诊断能力和治疗选择,最终为改善火鸡群体的健康状况做出贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebd5/12457859/66f4c0ac5a02/VMS3-11-e70605-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebd5/12457859/66f4c0ac5a02/VMS3-11-e70605-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebd5/12457859/66f4c0ac5a02/VMS3-11-e70605-g002.jpg

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Chronic pulmonary aspergillosis: comprehensive insights into epidemiology, treatment, and unresolved challenges.慢性肺曲霉病:关于流行病学、治疗及未解决挑战的全面见解
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Mitigation Potential of Herbal Extracts and Constituent Bioactive Compounds on in Meat-Type Poultry.草药提取物及生物活性成分对肉用型家禽的缓解潜力
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Response of broilers to dietary inclusion of atoxigenic strain as a biocontrol strategy of aflatoxin.
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IFN-γ Limits Immunopathogenesis but Delays Fungal Clearance during Pneumocystis Pneumonia.IFN-γ 限制免疫病理发生,但延迟肺孢子菌肺炎时真菌清除。
J Immunol. 2023 Nov 1;211(9):1397-1405. doi: 10.4049/jimmunol.2300460.
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Overcoming clinical challenges in the management of invasive fungal infections in low- and middle-income countries (LMIC).应对低收入和中等收入国家侵袭性真菌感染管理中的临床挑战。
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A critical assessment of the cellular defences of the avian respiratory system: are birds in general and poultry in particular relatively more susceptible to pulmonary infections/afflictions?对禽类呼吸系统细胞防御机制的批判性评估:一般鸟类,特别是家禽是否更容易受到肺部感染/疾病的影响?
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Calcineurin: The Achilles' heel of fungal pathogens.钙调神经磷酸酶:真菌病原体的致命弱点。
PLoS Pathog. 2023 Jul 6;19(7):e1011445. doi: 10.1371/journal.ppat.1011445. eCollection 2023 Jul.
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Aspergillosis: an Update on Clinical Spectrum, Diagnostic Schemes, and Management.曲霉病:临床谱、诊断方案及管理的最新进展
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Coccidioidomycosis and Host Microbiome Interactions: What We Know and What We Can Infer from Other Respiratory Infections.球孢子菌病与宿主微生物组相互作用:我们所知道的以及我们能从其他呼吸道感染中推断出的内容。
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