James A E, Novak G R, Strecker E P, Flor W J
Radiology. 1977 Nov;125(2):417-20. doi: 10.1148/125.2.417.
The central canal of the spinal cord in certain animal species has been shown to be an alternative pathway of cerebrospinal fluid flow in experimentally induced hydrocephalus. Enlargement and increased movement of cerebrospinal fluid in the central canal has been proposed as a compensatory mechanism in hydrocephalus in humans. The central canal of the spinal cord was normal in 5 dogs and 2 primates made hydrocephalic by a relatively atraumatic experimental model which simulates the human disorder to chronic communicating hydrocephalus. Dilatation of the central canal is apparently not an important compensatory alternative pathway.
在某些动物物种中，脊髓中央管已被证明在实验性诱导脑积水时是脑脊液流动的替代途径。有人提出脊髓中央管中脑脊液的扩大和流动增加是人类脑积水的一种代偿机制。通过一种相对无创的实验模型使5只狗和2只灵长类动物发生脑积水，该模型模拟人类慢性交通性脑积水疾病，结果发现这些动物的脊髓中央管是正常的。脊髓中央管的扩张显然不是一个重要的代偿性替代途径。
