James A E, Flor W J, Novak G R, Strecker E P, Burns B
J Neurosurg. 1978 Jun;48(6):970-4. doi: 10.3171/jns.1978.48.6.0970.
The central canal of the spinal cord has been proposed as a significant compensatory alternative pathway of cerebrospinal fluid (CSF) flow in hydrocephalus. Ten dogs were made hydrocephalic by a relatively atraumatic experimental model that simulates the human circumstance of chronic communicating hydrocephalus. The central canal was studied by histopathology and compared with 10 normal control dogs. In both groups the central canal of the spinal cord was normal in size, configuration, and histological appearance. In this experimental model dilatation of the canal and increased movement of CSF does not appear to be a compensatory alternative pathway.
脊髓中央管已被提出作为脑积水时脑脊液（CSF）流动的一个重要代偿性替代途径。通过一种相对无创的实验模型使10只狗发生脑积水，该模型模拟了人类慢性交通性脑积水的情况。通过组织病理学研究脊髓中央管，并与10只正常对照狗进行比较。两组中脊髓中央管在大小、形态和组织学外观上均正常。在这个实验模型中，中央管扩张和脑脊液流动增加似乎不是一个代偿性替代途径。
