Wickramasekera Ian
Department of Psychiatry and Behavioral Sciences, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
Brain Sci. 2025 Sep 2;15(9):955. doi: 10.3390/brainsci15090955.
Threat activation or deactivation in the brain-body is associated with nocebo or placebo induced by medical-surgical procedures. Some originate as nocebo and can become 30-50% of presentations to primary care physicians. Patients with FSD medical-surgical services, despite the and are at risk for from . The Conditioned Response Model () of postulates three mechanisms, by , which drive placebo and nocebo and FSD. The High Risk Model of Threat Perception postulates that , driving . and the of and are postulated to , . a large (N = 6,891) sample of patients with . A total of 50% of patients with with chronic pain (n = 224) had a ) during experimental induction. The HRMTP predicts that PTI associated with is associated with the . This prediction was confirmed. Learning predicts that activation by can nocebo and FSD and can placebo effects in clinician-patient relationships. Identifying that enables the diagnosis of FSD by and not simply by .
大脑 - 身体中的威胁激活或失活与医疗 - 外科手术诱导的反安慰剂或安慰剂效应相关。一些最初表现为反安慰剂效应，在向初级保健医生就诊的病例中可占30% - 50%。患有性功能障碍（FSD）的患者接受医疗 - 外科服务，尽管存在……且有因……而面临风险。条件反应模型（）假设了三种机制，通过这些机制驱动安慰剂和反安慰剂效应以及性功能障碍。威胁感知的高风险模型假设……，驱动……。并且假设……和……的……会……，……。对一大群（N = 6891）患有……的患者进行了研究。共有50%患有慢性疼痛的患者（n = 224）在实验诱导期间出现了（）。高风险威胁感知模型（HRMTP）预测与……相关的疼痛阈值指数（PTI）与……相关。这一预测得到了证实。学习理论预测，通过……激活……可引发反安慰剂效应和性功能障碍，并且可在医患关系中引发安慰剂效应。识别出……能够通过……而非仅仅通过……来诊断性功能障碍。
