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我们在蜱传疾病疫苗研发方面处于什么阶段?

What Stage Are We at in the Development of Vaccines Against Tick-Borne Diseases?

作者信息

Stachera Weronika, Szuba Magdalena, Kim Arya Taesung, Yu Subin, Choi Jaeuk, Nzekea Deborah, Wu Yen Ching, Brzozowska Adrianna, Sota Marcin, Misiak Marianna, Dybicz Monika

机构信息

Department of General Biology and Parasitology, Medical University of Warsaw, 02-004 Warsaw, Poland.

出版信息

Vaccines (Basel). 2025 Sep 22;13(9):990. doi: 10.3390/vaccines13090990.

Abstract

The increasing prevalence of Lyme disease, tick-borne encephalitis (TBE), and other tick-borne infections such as , , , and is a growing public health concern. Existing tick bite prevention strategies are insufficient; therefore, vaccines represent a promising preventive measure. At the moment, only a vaccine for tick-borne encephalitis is available on the market. A vaccine for Lyme disease, however, is at an advanced stage of clinical trials. In this article, we focus on describing the progress in the invention of vaccines for tick-borne diseases. This article analyzes their development and effectiveness.

摘要

莱姆病、蜱传脑炎(TBE)以及其他蜱传感染(如 、 、 、 )的患病率不断上升,这日益引起了公共卫生领域的关注。现有的蜱虫叮咬预防策略并不充分;因此,疫苗是一种很有前景的预防措施。目前,市场上仅有一款针对蜱传脑炎的疫苗。然而,一款针对莱姆病的疫苗正处于临床试验的后期阶段。在本文中,我们着重描述蜱传疾病疫苗的研发进展。本文分析了它们的发展情况及其有效性。

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