Solov'ev V D, Nekliudova L I, Fedorova Iu B, Gumennik A E, Kitsak V Ia
Vopr Virusol. 1977(1):29-32.
A comparative examination of 226 paired sera from patients with pneumonia was carried out by CFT, HI, neuraminidase activity inhibition (NI) and double immunodiffusion. A correlation of the results of agar gel precipitation and the CFT and HI tests was observed. Convalescent sera contained antibody to influenza virus ribonucleoprotein frequently, less so to its neuraminidase or hemagglutinin. The precipitation test was shown to be highly sensitive, easy to perform, and therefore should be used in examinations of sera from patients with influenza-bacterial pneumonia.
采用补体结合试验(CFT)、血凝抑制试验(HI)、神经氨酸酶活性抑制试验(NI)和双向免疫扩散法,对226例肺炎患者的配对血清进行了对比检测。观察到琼脂凝胶沉淀试验结果与补体结合试验和血凝抑制试验结果之间存在相关性。恢复期血清中经常含有针对流感病毒核糖核蛋白的抗体,针对其神经氨酸酶或血凝素的抗体则较少。沉淀试验显示出高度敏感性,易于操作,因此应用于流感-细菌性肺炎患者血清的检测。