Zhou Junfeng, Su Yingjie, He Liudang, Ding Ning, Zeng Zhao
Endoscopic Medical Center, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University / Hunan Cancer Hospital, Changsha, HN, China.
Department of Emergency Medicine, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, HN, China.
Clin Exp Hypertens. 2025 Dec 31;47(1):2563779. doi: 10.1080/10641963.2025.2563779. Epub 2025 Sep 29.
This study investigated the association between several dietary quality scores-including the healthy eating index-2015(HEI-2015), dietary inflammatory index (DII), and dietary approaches to stop hypertension (DASH)-and the risk of cardiovascular disease(CVD) mortality in hypertension treatment group.
Data were obtained from 11,310 participants in the the U.S. Centers for Disease Control and Prevention's National Health and Nutrition Examination Survey (1999-2016). Diet quality scores were calculated based on the type and quantity of food and beverages consumed by participants in the past 24 h. CVD mortality was defined as deaths from heart or cerebrovascular disease (ICD-10). We used cox proportional hazards regression to assess the association between diet quality scores and CVD mortality.
During an average follow-up period of 109 months, 1324 deaths from CVD were confirmed. HEI-2015 and DII showed statistically significant negative association (HR, 0.9404 (95% CI = 0.8846, 0.9998), = 0.0491) and positive correlation (HR, 1.0514 (95% CI = 1.0055, 1.0995), = 0.0278) with CVD mortality. DASH showed no statistically significant negative correlation with CVD mortality (HR, 0.9639 (95% CI = 0.9215, 1.0083), = 0.1096). However, trend tests for all three diet quality scores were significant (< 0.05).
The HEI-2015 and DASH dietary patterns reduce the risk of CVD mortality in the hypertension treatment group. In contrast, the DII dietary pattern increases the risk of CVD mortality in such patients.
本研究调查了包括2015年健康饮食指数(HEI - 2015)、饮食炎症指数(DII)和终止高血压饮食方法(DASH)在内的几种饮食质量评分与高血压治疗组心血管疾病(CVD)死亡率之间的关联。
数据来自美国疾病控制与预防中心的国家健康与营养检查调查(1999 - 2016年)中的11310名参与者。饮食质量评分是根据参与者在过去24小时内摄入的食物和饮料的类型及数量计算得出的。CVD死亡率定义为因心脏或脑血管疾病导致的死亡(国际疾病分类第十版,ICD - 10)。我们使用Cox比例风险回归来评估饮食质量评分与CVD死亡率之间的关联。
在平均109个月的随访期内,确认有1324例CVD死亡病例。HEI - 2015与CVD死亡率呈统计学显著负相关(风险比[HR],0.9404[95%置信区间(CI)=0.8846,0.9998],P = 0.0491),而DII与之呈正相关(HR,1.0514[95%CI = 1.0055,1.0995],P = 0.0278)。DASH与CVD死亡率无统计学显著负相关(HR,0.9639[95%CI = 0.9215,1.0083],P = 0.1096)。然而,所有三种饮食质量评分的趋势检验均具有显著性(P<0.05)。
HEI - 2015和DASH饮食模式可降低高血压治疗组的CVD死亡率。相比之下,DII饮食模式会增加此类患者的CVD死亡风险。