Manz F, Alatas H, Kochen W, Lutz P, Rebien W, Schärer K
Arch Dis Child. 1977 Sep;52(9):721-4. doi: 10.1136/adc.52.9.721.
In 15 children with advanced chronic renal failure, glomerular filtration rate was determined by different methods. Inulin clearance correlated well with the mean of creatinine and urea clearance, and also with 51-chromium edetic acid (EDTA) clearance measured over 24 hours. The absolute values of creatinine clearance and of 51Cr-EDTA clearance measured up to 8 hours were higher than inulin clearance. In advanced renal failure both the 51Cr-EDTA clearance measured over 24 hours, and the mean of creatinine and urea clearance, provide acceptable estimates of true glomerular filtration rate.
对15名晚期慢性肾衰竭患儿采用不同方法测定肾小球滤过率。菊粉清除率与肌酐清除率和尿素清除率的均值相关性良好，也与24小时测定的51-铬依地酸（EDTA）清除率相关性良好。长达8小时测定的肌酐清除率和51Cr-EDTA清除率的绝对值高于菊粉清除率。在晚期肾衰竭中，24小时测定的51Cr-EDTA清除率以及肌酐清除率和尿素清除率的均值，均可对真实肾小球滤过率提供可接受的估计值。
