同种核物质的促有丝分裂作用。
The mitogenic effects of isologous nuclear material.
作者信息
Pegrum G D, Perera D J, Thompson E
出版信息
Immunology. 1972 Jul;23(1):13-8.
Abstract
The nuclear material from human lymphocytes stimulated with phytohaemagglutinin (PHA) will produce a marked increase of DNA synthesis in unstimulated isologous lymphocytes which is far in excess of the normal response to PHA by the same lymphocytes. It is postulated that release of nuclear complexes from a few lymphocytes transformed in response to a specific stimulus is responsible for the transformation produced in surrounding lymphocytes which are non-responsive to the initial antigenic challenge.
摘要
用植物血凝素（PHA）刺激的人淋巴细胞的核物质，会使未受刺激的同源淋巴细胞的DNA合成显著增加，这远远超过相同淋巴细胞对PHA的正常反应。据推测，对特定刺激产生反应而转化的少数淋巴细胞释放的核复合物，是导致周围对初始抗原刺激无反应的淋巴细胞发生转化的原因。
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引用本文的文献
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The immunogenic and co-operative effects of lymphocyte nuclear material from antigen-primed mice.来自抗原致敏小鼠的淋巴细胞核物质的免疫原性及协同效应。
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