Schmidt N J, Roberto R R, Lennette E H
Infect Immun. 1972 Jul;6(1):1-4. doi: 10.1128/iai.6.1.1-4.1972.
"Australia" (Au) antigens from various groups of individuals were examined for the presence of d and y determinants. Antigens from all of the 214 individuals examined were found to possess either the d or y determinant, in addition to the a determinant. With the ay antiserum employed, antibody absorption was found to be a more effective means than demonstration of spur formation for detection of the y determinant. Antigens with ad specificity predominated in a collection of sera from non-ill Tongan children and adults, but no significant differences were noted in the specificities of antigens from individuals from four different regions. Almost all of the antigens from various groups of individuals in California, including inmates of a state hospital, a group of heroin users, and hepatitis patients from San Francisco General Hospital, were of the ay specificity. With one exception, antigenic specificities were found to persist for 3 years in a group of Tongan school children. Specificities also persisted in chronic carriers from California and in hepatitis patients over the course of antigenemia. Of 15 human and 4 animal antisera examined, antibodies to the y determinant were demonstrable only in a single (human) antiserum, and antibodies to the d determinant were demonstrable in one guinea pig antiserum and one horse antiserum.
检测了来自不同人群的“澳大利亚”（Au）抗原中d和y决定簇的存在情况。在所检测的214个人的所有抗原中，除a决定簇外，均发现含有d或y决定簇。在所使用的ay抗血清中，发现抗体吸收是检测y决定簇比显示刺突形成更有效的方法。在来自健康汤加儿童和成人的一组血清中，具有ad特异性的抗原占主导，但来自四个不同地区的个体的抗原特异性未发现显著差异。加利福尼亚不同人群的几乎所有抗原，包括一家州立医院的住院患者、一组海洛因使用者以及旧金山综合医院的肝炎患者，均具有ay特异性。有一个例外，在一组汤加学童中发现抗原特异性持续了3年。在加利福尼亚的慢性携带者和肝炎患者的抗原血症过程中，特异性也持续存在。在所检测的15种人抗血清和4种动物抗血清中，仅在一种（人）抗血清中可检测到针对y决定簇的抗体，在一种豚鼠抗血清和一种马抗血清中可检测到针对d决定簇的抗体。
