Margni R A, Castrelos O D, Paz C B
Immunology. 1973 May;24(5):781-9.
The results obtained in the quantification of γ and γ anti-hapten (DNP) and anti-carrier (HGG) antibodies obtained weekly during 50 weeks and proceeding from a group of three Merino sheep immunized with DNP—HGG, are described. The primary and secondary response and the antibody variations in weekly repeated stimulations were studied. The anti-DNP and anti-HGG total antibodies have similar variations. γ and γ anti-DNP and anti-HGG antibodies do not show differences in the primary response nor in weekly repeated stimulations. In the secondary response, a high increase of γ with loss of γ is observed. After a certain time γ decreases and γ increases.
描述了在50周内每周对一组三只用二硝基苯-人γ球蛋白（DNP-HGG）免疫的美利奴绵羊进行γ和γ抗半抗原（DNP）及抗载体（HGG）抗体定量所获得的结果。研究了初次和二次反应以及每周重复刺激时抗体的变化。抗DNP和抗HGG总抗体有相似的变化。γ和γ抗DNP及抗HGG抗体在初次反应和每周重复刺激中均未显示出差异。在二次反应中，观察到γ显著增加而γ减少。经过一定时间后，γ减少而γ增加。
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