硬骨鱼中的半抗原-载体效应。
The hapten-carrier effect in teleost fish.
作者信息
Yocum D, Cuchens M, Clem L W
出版信息
J Immunol. 1975 Mar;114(3):925-7.
PMID:46263
Abstract
The sea robin (Prionotus evolans), a representative teleost fish, was found to undergo the hapten-carrier effect, suggestive of T-B cell cooperativity, in vivo with dinitrophenyl as the hapten and bovine gamma-globulin or bovine serum albumin as carriers. In contrast to mammalian systems, the secondary anti-hapten response in the sea robin was found to involve exclusively high molecular weight antibody.
摘要
鲂鮄（Prionotus evolans）是一种典型的硬骨鱼，研究发现，以二硝基苯基作为半抗原，牛γ球蛋白或牛血清白蛋白作为载体时，鲂鮄在体内会发生半抗原-载体效应，提示T细胞与B细胞的协同作用。与哺乳动物系统不同，鲂鮄的二次抗半抗原反应被发现仅涉及高分子量抗体。
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