人嗜碱性粒细胞的趋化作用。
Chemotaxis of human basophil leucocytes.
作者信息
Kay A B, Austen K F
出版信息
Clin Exp Immunol. 1972 Aug;11(4):557-63.
Abstract
Human peripheral blood basophils from two patients with unusually high basophil counts in association with chronic myelogenous leukaemia migrated toward various chemotactic agents of human origin. These included supernatants from sensitized lymphocytes challenged with specific antigen, diffusates from lung fragments challenged with pollen antigen E, the enzyme plasma kallikrein, and two complement derived agents, C5a and C[unk][unk][unk]. Thus, chemotaxis , a previously unreported property of human basophils, has been observed, although none of the agents tested produced a selective chemotactic response.
摘要
来自两名慢性粒细胞白血病患者且嗜碱性粒细胞计数异常高的人外周血嗜碱性粒细胞，向多种人源趋化剂迁移。这些趋化剂包括用特异性抗原刺激的致敏淋巴细胞的上清液、用花粉抗原E刺激的肺组织碎片的扩散物、酶血浆激肽释放酶，以及两种补体衍生剂C5a和C[unk][unk][unk]。因此，尽管所测试的趋化剂均未产生选择性趋化反应，但已观察到趋化作用，这是人类嗜碱性粒细胞以前未报道过的特性。
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