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老年人的长期合成代谢疗法。

Long-term anabolic therapy in the elderly.

作者信息

Lye M D, Ritch A E

出版信息

Age Ageing. 1977 Nov;6(4):221-7. doi: 10.1093/ageing/6.4.221.

DOI:10.1093/ageing/6.4.221
PMID:413345
Abstract

The anabolic agent stanozolol has been used to increase weight and activity in the elderly, but its long-term effect are largely unknown. A double-blind trial of stanozolol against placebo was continued for 12 months. Measuremtnes of weight, fat, fat-free mass, behaviour and activity were made at regular intervals, plus detailed biochemical and haematological profiles. There were no differences between the two groups in respect of weight, fat, fat-free mass and activity levels. There were significant increases in haemoglobin at six and 12 months and packed cell volume at 12 months in the active group. No androgenic side-effect were encountered.

摘要

合成代谢药物司坦唑醇曾被用于增加老年人的体重和活动能力,但其长期效果在很大程度上尚不清楚。一项针对司坦唑醇与安慰剂的双盲试验持续了12个月。定期测量体重、脂肪、去脂体重、行为和活动情况,同时还进行详细的生化和血液学检查。两组在体重、脂肪、去脂体重和活动水平方面没有差异。活性组在6个月和12个月时血红蛋白显著增加,在12个月时红细胞压积显著增加。未出现雄激素副作用。

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