Genizi Jacob, Mansour Raneen, Burbara Malak, Gal Shoshana, Nathan Keren, Kaly Lisa, Yaniv Liat
Pediatric Department, Bnai Zion Medical Center, Haifa 3104802, Israel.
Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525422, Israel.
Healthcare (Basel). 2025 Dec 3;13(23):3158. doi: 10.3390/healthcare13233158.
The aim of our study was to compare two questionnaires regarding their ability to globally assess the impact of headaches on daily functioning in children as a primary endpoint and, secondarily, to evaluate their correlation to frequency and headache strength. Headache is a common complaint in children and adolescents, leading to functional impairment. The impact of primary headaches, such as migraine and tension-type headaches, varies according to pain severity and frequency. Although the PedMIDAS questionnaire is a validated tool for assessing headache-related impact in children, it can be difficult for children to complete. The HIT-6 questionnaire is user-friendly but has been validated exclusively for use in adults. Our method involved a prospective cohort study in children aged 6-18 years who visited the headache clinic at Bnai Zion Medical Center due to primary headaches. All children filled in both the PedMIDAS and HIT-6. Data on headache diagnosis, frequency and intensity along with demographic data were obtained. Of the 100 children participating, 96 completed both questionnaires. The final sample was 66% (63) female, and the average age was 14 years (±3.3). Migraine was reported by 62% (60), followed by tension-type headaches (18%) and mixed headache (15%). A weak positive spearman correlation was observed between PedMIDAS and HIT-6 scores to age (respectively, ρ 0.3 with value < 0.005, and ρ 0.2 with value < 0.05), a weak positive spearman correlation as well between the HIT-6 score and both disease duration and headache intensity (respectively, ρ 0.221 with value < 0.05 and ρ 0.250 with value < 0.05). PedMIDAS score was weakly positively correlated to headache frequency (ρ 0.27 with value < 0.05). A moderately positive spearman correlation was found between the PedMIDAS and HIT scores with ρ 0.6 and value < 0.005. Linear regression analysis revealed a stronger correlation with headache frequency for the HIT-6 than for the PedMIDAS, when adjusted to gender and headache type. The HIT-6 questionnaire correlates with the PedMIDAS questionnaire and can serve as a good alternative for easily evaluating headache burden in children.
我们研究的目的是比较两份问卷，将其全面评估头痛对儿童日常功能影响的能力作为主要终点，其次评估它们与头痛频率和强度的相关性。头痛是儿童和青少年的常见主诉，会导致功能损害。偏头痛和紧张型头痛等原发性头痛的影响因疼痛严重程度和频率而异。虽然PedMIDAS问卷是评估儿童头痛相关影响的有效工具，但儿童可能难以完成。HIT-6问卷对用户友好，但仅在成人中得到验证。我们的方法涉及对6至18岁因原发性头痛前往贝纳伊锡安医疗中心头痛门诊就诊的儿童进行前瞻性队列研究。所有儿童都填写了PedMIDAS和HIT-6问卷。获取了头痛诊断、频率和强度的数据以及人口统计学数据。在参与研究的100名儿童中，96名完成了两份问卷。最终样本中66%（63名）为女性，平均年龄为14岁（±3.3岁）。报告患有偏头痛的占62%（60名），其次是紧张型头痛（18%）和混合型头痛（15%）。PedMIDAS和HIT-6得分与年龄之间存在弱正斯皮尔曼相关性（分别为ρ0.3，P值<0.005；以及ρ0.2，P值<0.05），HIT-6得分与病程和头痛强度之间也存在弱正斯皮尔曼相关性（分别为ρ0.221，P值<0.05；以及ρ0.250，P值<0.05）。PedMIDAS得分与头痛频率呈弱正相关（ρ0.27，P值<0.05）。PedMIDAS和HIT得分之间发现中度正斯皮尔曼相关性，ρ为0.6，P值<0.005。线性回归分析显示，在根据性别和头痛类型进行调整后，HIT-6与头痛频率的相关性比PedMIDAS更强。HIT-6问卷与PedMIDAS问卷相关，可作为轻松评估儿童头痛负担的良好替代工具。
