炎症中中性粒细胞迁移的天然介质。II. 白细胞趋素与免疫球蛋白G的共同抗原性。
The natural mediator for PMN emigration in inflammation. II. Common antigenicity of leucoegresin with immunoglobulin G.
作者信息
Yamamoto S, Yoshinaga M, Hayashi H
出版信息
Immunology. 1971 May;20(5):803-8.
Abstract
A chemotactic factor (leucoegresin) for PMN was extracted from the inflamed skin of rabbits and purified. Agar immunoelectrophoresis and immunodiffusion using goat antiserum against rabbit serum and against rabbit IgG or Fc revealed that rabbit leucoegresin shared at least some antigenic determinants with rabbit IgG. Furthermore, the chemotactic activity of leucoegresin disappeared from the fluid phase when it reacted with goat antibody.
摘要
从兔的炎症皮肤中提取并纯化了一种针对中性粒细胞的趋化因子（白细胞趋化素）。使用山羊抗兔血清以及抗兔IgG或Fc的抗血清进行琼脂免疫电泳和免疫扩散试验，结果显示兔白细胞趋化素与兔IgG至少共享一些抗原决定簇。此外，当白细胞趋化素与山羊抗体反应时，其趋化活性在液相中消失。
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