β-肾上腺素能受体阻断对人体出汗的影响。
The effect of -adrenoceptor blockade on human sweating.
作者信息
Allen J A, Jenkinson D J, Roddie I C
出版信息
Br J Pharmacol. 1973 Mar;47(3):487-97. doi: 10.1111/j.1476-5381.1973.tb08180.x.
Abstract
- Changes in cutaneous water loss were followed by continuously monitoring total body weight loss.2. Sweating was induced in normal subjects by raising the environmental temperature or by subjecting them to the emotional stress of mental arithmetic.3. Propranolol in a dosage of 0.15 mg/kg body weight intravenously had no significant effect on either thermal or emotional sweating, whereas thermal sweating was completely blocked temporarily by administration of atropine 2.4 mg intravenously.4. It is concluded that beta-adrenoceptor blockade has no effect on physiological sweating in normal people.
摘要
通过持续监测总体重减轻来跟踪皮肤水分流失的变化。
通过提高环境温度或让正常受试者承受心算的情绪压力来诱导出汗。
静脉注射剂量为0.15毫克/千克体重的普萘洛尔对热汗或情绪性出汗均无显著影响，而静脉注射2.4毫克阿托品可暂时完全阻断热汗。
得出的结论是，β-肾上腺素能受体阻断对正常人的生理性出汗没有影响。
相似文献
1
The effect of -adrenoceptor blockade on human sweating.β-肾上腺素能受体阻断对人体出汗的影响。
Br J Pharmacol. 1973 Mar;47(3):487-97. doi: 10.1111/j.1476-5381.1973.tb08180.x.
2
Effect of beta-adrenoceptor blockade on thermoregulation during prolonged exercise.β-肾上腺素能受体阻断对长时间运动期间体温调节的影响。
J Appl Physiol (1985). 1985 Mar;58(3):899-906. doi: 10.1152/jappl.1985.58.3.899.
3
Effect of beta-adrenoceptor blockade and calcium antagonism, alone and in combination, on thermoregulation during prolonged exercise.β-肾上腺素能受体阻滞剂与钙拮抗剂单独及联合使用对长时间运动期间体温调节的影响。
Int J Sports Med. 1987 Feb;8(1):1-5. doi: 10.1055/s-2008-1025631.
4
β-Adrenergic receptor blockade does not modify non-thermal sweating during static exercise and following muscle ischemia in habitually trained individuals.β-肾上腺素能受体阻断剂并不改变习惯性训练个体在静息运动期间和肌肉缺血后的非热出汗。
Eur J Appl Physiol. 2018 Dec;118(12):2669-2677. doi: 10.1007/s00421-018-3993-x. Epub 2018 Sep 20.
5
The role of circulating catecholamines in sweat production in man.循环儿茶酚胺在人体汗液分泌中的作用。
J Physiol. 1972 Dec;227(3):801-14. doi: 10.1113/jphysiol.1972.sp010059.
6
Sweat production during catecholamine infusion in man.
J Physiol. 1972 Apr;222(1):70P-71P.
7
Evidence for β-adrenergic modulation of sweating during incremental exercise in habitually trained males.在习惯训练的男性进行递增运动期间，β-肾上腺素能调节出汗的证据。
J Appl Physiol (1985). 2017 Jul 1;123(1):182-189. doi: 10.1152/japplphysiol.00220.2017. Epub 2017 May 4.
8
Studies on sweating in clinical and experimental thyrotoxicosis.
Clin Sci Mol Med. 1973 Dec;45(6):765-73. doi: 10.1042/cs0450765.
9
The cholinergic blockade of both thermally and non-thermally induced human eccrine sweating.热诱导和非热诱导的人汗腺分泌的胆碱能阻断作用。
Exp Physiol. 2012 Aug;97(8):930-42. doi: 10.1113/expphysiol.2012.065037. Epub 2012 Apr 11.
10
Comparison of atenolol and propranolol during insulin-induced hypoglycaemia.阿替洛尔与普萘洛尔在胰岛素诱导的低血糖期间的比较。
Br Med J. 1976 Jul 31;2(6030):272-3. doi: 10.1136/bmj.2.6030.272.
引用本文的文献
1
β-Adrenergic receptor blockade does not modify non-thermal sweating during static exercise and following muscle ischemia in habitually trained individuals.β-肾上腺素能受体阻断剂并不改变习惯性训练个体在静息运动期间和肌肉缺血后的非热出汗。
Eur J Appl Physiol. 2018 Dec;118(12):2669-2677. doi: 10.1007/s00421-018-3993-x. Epub 2018 Sep 20.
2
The effect of β-adrenoceptor blockade on body temperature and plasma renin activity in heat-exposed man.β-肾上腺素能受体阻断对高温环境下人体体温和血浆肾素活性的影响。
Br J Clin Pharmacol. 1974 Aug;1(4):307-12. doi: 10.1111/j.1365-2125.1974.tb00258.x.
3
The effect of antidiuretic hormone on human sweating.抗利尿激素对人体出汗的影响。
J Physiol. 1974 Jan;236(2):403-12. doi: 10.1113/jphysiol.1974.sp010442.
4
The regional distribution of emotional sweating in man.人类情感性出汗的区域分布。
J Physiol. 1973 Dec;235(3):749-59. doi: 10.1113/jphysiol.1973.sp010414.
5
The effect of pain on human sweating.疼痛对人体出汗的影响。
J Physiol. 1973 Dec;235(3):741-7. doi: 10.1113/jphysiol.1973.sp010413.
6
Human responses to emotional stress.人类对情绪压力的反应。
Ir J Med Sci. 1977 Dec;146(12):395-417. doi: 10.1007/BF03030998.
本文引用的文献
1
The nervous and chemical control of sweating.出汗的神经与化学控制。
Br J Dermatol. 1952 Feb;64(2):43-54. doi: 10.1111/j.1365-2133.1952.tb16160.x.
2
THE EFFECTS ON CARDIAC MUSCLE OF BETA-RECEPTOR ANTAGONISTS IN RELATION TO THEIR ACTIVITY AS LOCAL ANAESTHETICS.β受体拮抗剂对心肌的作用与其作为局部麻醉剂的活性的关系。
Br J Pharmacol Chemother. 1965 Apr;24(2):332-8. doi: 10.1111/j.1476-5381.1965.tb01719.x.
3
THE CHRONOTROPIC AND VAGAL-BLOCKING ACTIONS OF NAPHTHYLISOPROTERENOL STUDIED BY DIRECT PERFUSION OF THE SINUS NODE.
J Pharmacol Exp Ther. 1964 Mar;143:350-5.
4
Chronotropic and vagal-blocking effects of DCI studied by direct perfusion of the sinus node.
J Pharmacol Exp Ther. 1963 Apr;140:73-8.
5
Insensible weight loss at high skin temperatures.
J Appl Physiol. 1957 Jul;11(1):41-4. doi: 10.1152/jappl.1957.11.1.41.
6
Influence of the rate of sweating on the inhibitory dose of atropine.
J Appl Physiol. 1967 Apr;22(4):648-54. doi: 10.1152/jappl.1967.22.4.648.
7
Effects of cholinergic and adrenergic blocking agents on the activity of the eccrine sweat glands.胆碱能和肾上腺素能阻断剂对小汗腺活动的影响。
J Physiol. 1970 Nov;210(4):883-95. doi: 10.1113/jphysiol.1970.sp009247.
8
A body balance to measure sweat rates in man.
Biomed Eng. 1971 Oct;6(10):468-71.
9
The role of circulating catecholamines in sweat production in man.循环儿茶酚胺在人体汗液分泌中的作用。
J Physiol. 1972 Dec;227(3):801-14. doi: 10.1113/jphysiol.1972.sp010059.
10
Effect of five beta-adrenoceptor antagonists on the effect of isoprenaline and acetylcholine on human isolated smooth muscle.五种β-肾上腺素能受体拮抗剂对异丙肾上腺素和乙酰胆碱作用于人体离体平滑肌的影响。
Br J Pharmacol. 1971 Feb;41(2):426P-427P.
Zotero 插件