Valić F, Zuskin E
Br J Ind Med. 1973 Oct;30(4):381-4. doi: 10.1136/oem.30.4.381.
381-384. The protective effect of the preshift application of a bronchodilator (orciprenaline), an antihistamine drug (diadril), and ascorbic acid on flax-induced acute bronchoconstriction was studied in 13 byssinotic and 7 non-byssinotic female workers exposed to airborne fibres of biologically retted flax. Orciprenaline was applied by inhalation, while diadril and ascorbic acid were given orally. All the three drugs exerted a significant preventive effect, diminishing the acute fall of ventilatory capacity during the shift. The fall in forced expiratory volume (FEV) was reduced by 50% and the fall in maximal flow rate at 50% vital capacity (V̇ 50% VC) by over 65%.
381 - 384。研究了在13名患棉尘病的女工和7名未患棉尘病的女工中，预班前应用支气管扩张剂（间羟异丙肾上腺素）、抗组胺药（二乙氨乙醇）和抗坏血酸对亚麻诱导的急性支气管收缩的保护作用，这些女工暴露于生物脱胶亚麻的空气传播纤维中。间羟异丙肾上腺素通过吸入给药，而二乙氨乙醇和抗坏血酸则口服给药。这三种药物均发挥了显著的预防作用，减少了轮班期间通气能力的急性下降。用力呼气量（FEV）的下降减少了50%，50%肺活量时最大流速（V̇ 50% VC）的下降超过了65%。
