Jamison J P, Langlands J H, Lowry R C
Br J Ind Med. 1986 Dec;43(12):809-13. doi: 10.1136/oem.43.12.809.
A new method of retting flax recently developed to suit the United Kingdom climate has allowed the reintroduction of flax growing to this country. The weed killer glyphosate is sprayed on the crop which then rets before harvesting six weeks later. The acute bronchoconstrictor responses of 11 normal subjects to dust from dew retted and from pre-harvest retted flaxes were compared in a double blind crossover fashion. There were no significant differences in the dust levels nor in the size of the dust particles in the experimental dust room. The decreases in pulmonary function after six hours of dust inhalation were significantly larger after pre-harvest retted flax dust than after dew retted flax dust (delta FEV1, -0.21 and -0.40 1; delta MEF50, -0.72 and -1.211/s; delta sGaw (specific airway conductance), -0.17 and -0.65 kPa/s for dew retted and pre-harvest retted respectively). The subjects also reported more symptoms after inhaling pre-harvest retted flax dust. It is concluded that the acute bronchoconstrictor response to flax dust is increased by pre-harvest retting, suggesting an increased risk of byssinosis.
最近研发出一种适合英国气候的亚麻沤麻新方法，使得亚麻种植得以重新引入该国。将除草剂草甘膦喷洒在作物上，六周后收获前进行沤麻处理。以双盲交叉方式比较了11名正常受试者对露水沤麻亚麻和收获前沤麻亚麻粉尘的急性支气管收缩反应。实验粉尘室内的粉尘水平和粉尘颗粒大小均无显著差异。吸入粉尘6小时后，收获前沤麻亚麻粉尘导致的肺功能下降显著大于露水沤麻亚麻粉尘（第一秒用力呼气容积（FEV1）变化量分别为-0.21和-0.40升；50%用力呼气流量（MEF50）变化量分别为-0.72和-1.21升/秒；比气道传导率（sGaw）变化量分别为-0.17和-0.65千帕/秒，分别对应露水沤麻和收获前沤麻）。受试者吸入收获前沤麻亚麻粉尘后报告的症状也更多。得出的结论是，收获前沤麻会增加对亚麻粉尘的急性支气管收缩反应，提示棉尘病风险增加。
