谷氨酰胺合成酶对hut DNA转录的激活作用。
Activation of transcription of hut DNA by glutamine synthetase.
作者信息
Tyler B, Deleo A B, Magasanik B
出版信息
Proc Natl Acad Sci U S A. 1974 Jan;71(1):225-9. doi: 10.1073/pnas.71.1.225.
Abstract
The correct transcription of the hut (histidine utilization) operon DNA of Salmonella typhimurium requires activation either by 3':5'-cyclic adenosine monophosphate and catabolite-activating protein or by nonadenylylated glutamine synthetase (EC 6.3.1.2.). Thus, glutamine synthetase plays a regulatory role distinct from its enzymatic function.
摘要
鼠伤寒沙门氏菌的组氨酸利用（hut）操纵子DNA的正确转录需要3':5'-环磷酸腺苷和分解代谢物激活蛋白或未腺苷酸化的谷氨酰胺合成酶（EC 6.3.1.2）的激活。因此，谷氨酰胺合成酶发挥着与其酶功能不同的调节作用。
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