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Use of ultrasonic energy in assessing microbial contamination on surfaces.超声能量在评估表面微生物污染中的应用。
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Comparison of microbial contamination levels among hospital operating rooms and industrial clean rooms.
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Microbiological evaluation of the vacuum probe surface sampler.真空探头表面采样器的微生物学评估。
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A stochastic bioburden model for spacecraft sterilization.一种用于航天器灭菌的随机生物负载模型。
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通过体积空气采样对航天器表面微生物污染水平进行数学估计。

Mathematical estimation on the level of microbial contamination on spacecraft surfaces by volumetric air sampling.

作者信息

Oxborrow G S, Roark A L, Fields N D, Puleo J R

出版信息

Appl Microbiol. 1974 Apr;27(4):706-12. doi: 10.1128/am.27.4.706-712.1974.

DOI:10.1128/am.27.4.706-712.1974
PMID:4151118
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC380122/
Abstract

Microbiological sampling methods presently used for enumeration of microorganisms on spacecraft surfaces require contact with easily damaged components. Estimation of viable particles on surfaces using air sampling methods in conjunction with a mathematical model would be desirable. Parameters necessary for the mathematical model are the effect of angled surfaces on viable particle collection and the number of viable cells per viable particle. Deposition of viable particles on angled surfaces closely followed a cosine function, and the number of viable cells per viable particle was consistent with a Poisson distribution. Other parameters considered by the mathematical model included deposition rate and fractional removal per unit time. A close nonlinear correlation between volumetric air sampling and airborne fallout on surfaces was established with all fallout data points falling within the 95% confidence limits as determined by the mathematical model.

摘要

目前用于航天器表面微生物计数的微生物采样方法需要接触易受损部件。结合数学模型使用空气采样方法估算表面上的活菌颗粒是可取的。数学模型所需的参数是倾斜表面对活菌颗粒收集的影响以及每个活菌颗粒中的活细胞数量。活菌颗粒在倾斜表面上的沉积紧密遵循余弦函数,并且每个活菌颗粒中的活细胞数量符合泊松分布。数学模型考虑的其他参数包括沉积速率和单位时间的去除分数。通过数学模型确定,所有沉降数据点均落在95%置信限内,从而建立了体积空气采样与表面空气沉降之间紧密的非线性相关性。