Carthew P, Verstraete A
Lab Anim. 1978 Jan;12(1):29-32. doi: 10.1258/002367778780953323.
This paper reports the results of a general survey, the first in the United Kingdom, carried out on accredited breeding colonies of mice, rats and guinea-pigs over a period of a year. While the results show the potential usefulness of a viral accreditation grading scheme, they also show that contamination of breeding colonies with inapparent viral infections is widespread. This situation can only be improved by the continuous monitoring of animal stocks for rodent viruses, with the aim of improving the standard of animals available for research and for pharmacological, toxicological and routine diagnostic procedures.
本文报告了一项全面调查的结果,这是在英国首次针对小鼠、大鼠和豚鼠的认可繁殖群体进行的为期一年的调查。虽然结果显示了病毒认可分级方案的潜在用途,但也表明繁殖群体被隐性病毒感染污染的情况很普遍。只有通过持续监测动物种群中的啮齿动物病毒,以提高可用于研究以及药理、毒理和常规诊断程序的动物标准,这种情况才能得到改善。