仙台病毒在无胸腺裸鼠和无菌大鼠中的情况。
Sendai virus in nude and germ-free rats.
作者信息
Carthew P, Sparrow S
出版信息
Res Vet Sci. 1980 Nov;29(3):289-92. doi: 10.1016/S0034-5288(18)32629-8.
Abstract
The pathogenesis of Sendai virus infection was studied in athymic and AGUS rats. The infection was more severe in the athymic rats and caused considerable clinical disease. Virus was shown to replicate in the bronchial epithelium and persisted in athymic rats for the duration of the experiment (32 days). The characteristic changes of necrosis of the bronchial epithelium and subsequent hyperplasia also persisted in this group and was accompanied by quite extensive interstitial pneumonitis. The virus failed to evoke an antibody response in the athymic rats.
摘要
在无胸腺大鼠和无脾大鼠中研究了仙台病毒感染的发病机制。无胸腺大鼠的感染更为严重，并引发了相当严重的临床疾病。病毒在支气管上皮细胞中复制，并在无胸腺大鼠中在整个实验期间（32天）持续存在。支气管上皮细胞坏死及随后的增生等特征性变化在该组中也持续存在，并伴有相当广泛的间质性肺炎。病毒未能在无胸腺大鼠中引发抗体反应。
相似文献
1
Sendai virus in nude and germ-free rats.仙台病毒在无胸腺裸鼠和无菌大鼠中的情况。
Res Vet Sci. 1980 Nov;29(3):289-92. doi: 10.1016/S0034-5288(18)32629-8.
2
Naturally-occurring Sendai virus infection of athymic nude mice.无胸腺裸鼠的自然发生的仙台病毒感染。
Vet Pathol. 1976;13(1):36-46. doi: 10.1177/030098587601300105.
3
Exacerbation of murine respiratory mycoplasmosis in gnotobiotic F344/N rats by Sendai virus infection.仙台病毒感染加重悉生F344/N大鼠的鼠呼吸道支原体病
Vet Pathol. 1985 May;22(3):272-82. doi: 10.1177/030098588502200310.
4
[Symposium: Sendai virus infections in mouse-rat colonies. 1. Pathological observation].
Jikken Dobutsu. 1974 Oct;23(4):265-6.
5
Comparative lung pathology of inbred strain of mice resistant and susceptible to Sendai virus infection.对仙台病毒感染具有抗性和易感性的近交系小鼠的比较肺病理学
J Vet Med Sci. 1991 Apr;53(2):275-9. doi: 10.1292/jvms.53.275.
6
Persistence of pneumonia virus of mice and Sendai virus in germ-free (nu/nu) mice.小鼠肺炎病毒和仙台病毒在无菌（裸/裸）小鼠中的持续性。
Br J Exp Pathol. 1980 Apr;61(2):172-5.
7
Response of athymic nude mice to Sendai virus.
Jpn J Exp Med. 1979 Apr;49(2):123-30.
8
Establishment of a commercial production colony of Sprague-Dawley rats free of Sendai virus.无仙台病毒的斯普拉格-道利大鼠商业生产种群的建立。
Lab Anim Sci. 1987 Oct;37(5):666-7.
9
Acute and persistent alterations in pulmonary inflammatory cells and airway mast cells induced by Sendai virus infection in neonatal rats.
Vet Pathol. 1989 Jan;26(1):18-25. doi: 10.1177/030098588902600104.
10
Effect of sequential inoculations of Sendai virus and Pasteurella pneumotropica in mice.仙台病毒和嗜肺巴斯德氏菌先后接种对小鼠的影响。
J Am Vet Med Assoc. 1974 Apr 1;164(7):723-8.
引用本文的文献
1
2
Changes in epithelial secretory cells and potentiation of neurogenic inflammation in the trachea of rats with respiratory tract infections.呼吸道感染大鼠气管上皮分泌细胞的变化及神经源性炎症的增强
Anat Embryol (Berl). 1989;180(4):325-41. doi: 10.1007/BF00311165.
3
Mycoplasma pulmonis infections cause long-lasting potentiation of neurogenic inflammation in the respiratory tract of the rat.肺支原体感染可导致大鼠呼吸道神经源性炎症的长期增强。
J Clin Invest. 1991 Mar;87(3):787-99. doi: 10.1172/JCI115082.
本文引用的文献
1
Persistence of pneumonia virus of mice and Sendai virus in germ-free (nu/nu) mice.小鼠肺炎病毒和仙台病毒在无菌（裸/裸）小鼠中的持续性。
Br J Exp Pathol. 1980 Apr;61(2):172-5.
2
A comparison in germ-free mice of the pathogenesis of Sendai virus and mouse pneumonia virus infections.
J Pathol. 1980 Mar;130(3):153-8. doi: 10.1002/path.1711300303.
3
Hexamita and Giardia as a cause of mortality in congenitally thymus-less (nude) mice.六鞭毛虫属和贾第虫属作为先天性无胸腺（裸）小鼠死亡原因的研究
Clin Exp Immunol. 1973 Dec;15(4):623-7.
4
Hepatitis and brain lesions due to mouse hepatitis virus accompanied by wasting in nude mice.小鼠肝炎病毒引起的肝炎和脑损伤，伴有裸鼠消瘦。
Lab Anim. 1974 Sep;8(3):317-26. doi: 10.1258/002367774780943733.
5
The effect of cyclophosphamide on Sendai virus infection of mice.环磷酰胺对小鼠仙台病毒感染的影响。
J Med Microbiol. 1969 May;2(2):137-45. doi: 10.1099/00222615-2-2-137.
6
Natural history of Sendai virus infection in mice.小鼠仙台病毒感染的自然史。
Am J Epidemiol. 1968 Jul;88(1):112-25. doi: 10.1093/oxfordjournals.aje.a120859.
7
The natural history and immunopathology of outbred athymic (nude) mice.远交系无胸腺（裸）小鼠的自然病史和免疫病理学
Clin Immunol Immunopathol. 1975 Sep;4(3):324-40. doi: 10.1016/0090-1229(75)90002-1.
8
Experimental infection of adult axenic rats with Parker's rat coronavirus.用帕克大鼠冠状病毒对成年无菌大鼠进行实验性感染。
Arch Virol. 1977;54(4):345-52. doi: 10.1007/BF01314779.
9
Furunculosis in a mouse.小鼠的疖病。
Vet Rec. 1977 Nov 5;101(19):385. doi: 10.1136/vr.101.19.385.
10
A serological survey of accredited breeding colonies in the United Kingdom for common rodent viruses.对英国认可的繁殖群体进行的常见啮齿动物病毒血清学调查。
Lab Anim. 1978 Jan;12(1):29-32. doi: 10.1258/002367778780953323.
Zotero 插件