超氧化物与其他还原剂在生物产生羟基自由基过程中的比较。
Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals.
作者信息
Winterbourn C C
出版信息
Biochem J. 1979 Aug 15;182(2):625-8. doi: 10.1042/bj1820625.
Abstract
Iron--EDTA was shown to catalyse OH. production from H2O2 and ascorbate by a mechanism largely independent of superoxide. When ascorbate and superoxide were both present, the ascorbate mechanism was more important than superoxide as a source of OH., and would appear to be more significantly biologically.
摘要
铁-乙二胺四乙酸（Iron--EDTA）被证明可通过一种很大程度上独立于超氧化物的机制催化过氧化氢（H2O2）和抗坏血酸盐产生羟基自由基（OH.）。当抗坏血酸盐和超氧化物同时存在时，作为羟基自由基来源，抗坏血酸盐机制比超氧化物机制更重要，而且在生物学上似乎更显著。
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