Koeppen A H, Barron K D
Neurology. 1978 Mar;28(3):290-4. doi: 10.1212/wnl.28.3.290.
Marchiafava-Bignami disease was diagnosed postmortem in a 39-year-old man who drank excessive amounts of white port wine. This is the fifth report of the disease in a native North-American with no Italian ancestry. The lesion involved the corpus callosum and hippocampal commissure but spared the anterior commissure, middle cerebellar peduncles, optic chiasm, and centrum semiovale. Wernicke-Korsakoff encephalopathy and pellagroid neuronal changes were also present.
在一名饮用过量白波特酒的39岁男性身上,死后诊断出患有马基亚法瓦-比尼亚米病。这是北美本土一名无意大利血统患者患该疾病的第五份报告。病变累及胼胝体和海马连合,但未累及前连合、小脑中脚、视交叉和半卵圆中心。同时还存在韦尼克-科尔萨科夫脑病和类糙皮病性神经元改变。