正常淋巴细胞上同种异体抗原的细胞结合受体。II. 抗同种异体抗体血清含有与相关免疫活性T淋巴细胞发生反应的特异性因子。
Cell-bound receptors for alloantigens on normal lymphocytes. II. Antialloantibody serum contains specific factors reacting with relevant immunocompetent T lymphocytes.
作者信息
Binz H, Lindenmann J, Wigzell H
出版信息
J Exp Med. 1974 Sep 1;140(3):731-41. doi: 10.1084/jem.140.3.731.
Abstract
The rat popliteal node graft-vs.-host assay was shown to depend on the presence of parental T cells in the inoculum. Antialloantisera raised in F(1) hybrid rats against alloantibodies of one parent directed at transplantation antigens of the other parent displayed some or all of the following specific effects on parental T cells: They inhibited local GvH by purified T-cell suspensions; they blocked the capacity of GvH-reactive cells to adsorb onto fibroblast monolayers of the relevant genotype; together with complement, they killed GvH-reactive cells.
摘要
大鼠腘淋巴结移植物抗宿主试验表明，其依赖于接种物中亲代T细胞的存在。在F(1)杂种大鼠中产生的针对一方亲代针对另一方亲代移植抗原的同种抗体的抗同种抗血清，对亲代T细胞表现出以下部分或全部特异性作用：它们抑制纯化的T细胞悬液的局部移植物抗宿主反应；它们阻断移植物抗宿主反应性细胞吸附到相关基因型成纤维细胞单层上的能力；与补体一起，它们杀死移植物抗宿主反应性细胞。
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2
Clonal analysis of the T lymphocytes involved in parent versus F1 graft-versus-host reaction.参与亲代与F1代移植物抗宿主反应的T淋巴细胞的克隆分析。
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本文引用的文献
1
Cellular receptors. effect of anti-alloantiserum on the recognition of transplantation antigens.细胞受体。抗同种异体抗血清对移植抗原识别的影响。
J Exp Med. 1971 Nov 1;134(5):1083-94. doi: 10.1084/jem.134.5.1083.
2
Anti-alloantibodies: a de novo product.抗同种异体抗体：一种全新产物。
J Immunol. 1973 Oct;111(4):1108-11.
3
Cellular receptors: binding of radioactively labeled anti-alloantiserum.细胞受体：放射性标记抗同种异体血清的结合
J Exp Med. 1972 Oct 1;136(4):872-84. doi: 10.1084/jem.136.4.872.
4
Cell-bound receptors for alloantigens on normal lymphocytes. I. Characterization of receptor-carrying cells by the use of antibodies to alloantibodies.正常淋巴细胞上同种异体抗原的细胞结合受体。I. 利用抗同种抗体的抗体对携带受体的细胞进行特性鉴定。
J Exp Med. 1974 Apr 1;139(4):877-87. doi: 10.1084/jem.139.4.877.
5
Activation of T and B thymus cells to recognize histocompatibility antigens.T和B胸腺细胞被激活以识别组织相容性抗原。
Cell Immunol. 1973 Jul;8(1):177-83. doi: 10.1016/0008-8749(73)90106-8.
6
Fractionation of antigen reactive cells on a cellular immunoadsorbent: factors determining recognition of antigens by T-lymphocytes.在细胞免疫吸附剂上对抗抗原反应性细胞进行分级分离：决定T淋巴细胞对抗原识别的因素。
Proc Natl Acad Sci U S A. 1972 Jun;69(6):1620-4. doi: 10.1073/pnas.69.6.1620.
7
Graft-versus-host reactivity of lymphoid cells inhibited by anti-recognition structure serum.
Nat New Biol. 1972 Dec 13;240(102):214-5. doi: 10.1038/newbio240214a0.
8
The effects of anti-theta antiserum upon graft-versus-host activity of spleen and lymph node cells.抗θ抗血清对脾细胞和淋巴结细胞移植物抗宿主活性的影响。
Cell Immunol. 1972 Mar;3(3):461-9. doi: 10.1016/0008-8749(72)90251-1.
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A lymph node weight assay for the graft-versus-host activity of rat lymphoid cells.一种用于检测大鼠淋巴细胞移植物抗宿主活性的淋巴结重量测定法。
Transplantation. 1970 Sep;10(3):258-66. doi: 10.1097/00007890-197009000-00007.
10
T cells in recognition of histocompatibility antigens.
Nature. 1973 Dec 7;246(5432):351-2. doi: 10.1038/246351a0.
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