Minoli I, Moro G, Ovadia M F
Acta Paediatr Scand. 1978 Mar;67(2):161-8. doi: 10.1111/j.1651-2227.1978.tb16297.x.
Recent reports indicate that nasoduodenal feeding is a suitable technique for high risk newborns, in particular those with a low birth weight. In the period between February 1975 and June 1976, 100 high risk newborns, divided into four cohorts on the basis of birth weight in 500 g divisions, were fed by nasoduodenal tube. The effect of nasoduodenal feeding has been measured in several ways, but particularly consideration has been given to weight gain, its caloric cost, the mortality rates observed in the Unit before and after the introduction of this nutritional regime and complications. The use of nasoduodenal feeding abolished the physiological loss of weight which normally occurs during the first week of life and was associated with a subsequent rate of weight gain equal to or better than that observed in infants fed by other routes. The mean caloric intake was greater in smaller infants than in larger ones and it was accompanied by a steady decrease in weight gain per unit of caloric intake with increasing birth weight. In 1974 the overall mortality rate in the Unit was 18% and in 1975 following the introduction of nasoduodenal feeding fell to 11.4%. No serious complications were observed associated with nasoduodenal feeding. The conclusion is that this form of feeding is particularly suitable for infants with a birth weight of 1 500 g or less.
近期报告表明,鼻十二指肠喂养是高危新生儿,尤其是低出生体重儿的一种适宜喂养技术。在1975年2月至1976年6月期间,100名高危新生儿根据出生体重以500克为间隔分为四组,通过鼻十二指肠管进行喂养。鼻十二指肠喂养的效果通过多种方式进行了衡量,但特别考虑了体重增加、热量消耗、在引入这种营养方案前后该科室观察到的死亡率以及并发症情况。鼻十二指肠喂养消除了通常在出生后第一周出现的生理性体重下降,并且随后的体重增加速度与或优于通过其他途径喂养的婴儿。较小婴儿的平均热量摄入量比较大婴儿更高,并且随着出生体重增加,每单位热量摄入的体重增加量稳步下降。1974年该科室的总体死亡率为18%,1975年引入鼻十二指肠喂养后降至11.4%。未观察到与鼻十二指肠喂养相关的严重并发症。结论是这种喂养方式特别适合出生体重在1500克及以下的婴儿。