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通过鼻十二指肠喂养对婴儿幽门狭窄进行保守治疗。

Conservative management of infantile pyloric stenosis by nasoduodenal feeding.

作者信息

Yamashiro Y, Mayama H, Yamamoto K, Sato M, Nawate G

出版信息

Eur J Pediatr. 1981 May;136(2):187-92. doi: 10.1007/BF00441922.

DOI:10.1007/BF00441922
PMID:6785089
Abstract

Fifty cases of infantile plyoric stenosis were treated conservatively by transpyloric nasoduodenal tube feeding. The mean age on admission was 38.2 days. Transpyloric intubation was carried out in all patients and 45 (90%) with infantile pyloric stenosis were cured by nasuduodenal feeding. Among 5 (10%) requiring surgical intervention, abandonment of nasoduodenal feeding was the cause in only 3, and the parents chose an operation in the remaining 2 a few days after nasoduodenal feeding had been started. In non-surgically cured cases (45), mean body weights on admission and at discharge were 3,750 g and 5,177 g respectively; the duration of nasoduodenal feeding was 8 to 37 days (mean 17.2 days), mean weight gain during nasoduodenal feeding was 42.7 g/day and mean hospital stay was 39.7 days (38.0 days in 43 cases without any associated disorder). This experience suggests that nasoduodenal feeding in this report is a more effective treatment for infantile pyloric stenosis than any traditional medical treatment and it could be the preferred management in the small group of patients for whom an operation could carry a high risk, or whose parents refuse operation.

摘要

50例婴儿幽门狭窄患者通过经幽门鼻十二指肠管喂养进行保守治疗。入院时的平均年龄为38.2天。所有患者均进行了经幽门插管,45例(90%)婴儿幽门狭窄患者通过鼻十二指肠喂养治愈。在5例(10%)需要手术干预的患者中,仅3例是因为放弃鼻十二指肠喂养,其余2例是在开始鼻十二指肠喂养几天后家长选择了手术。在非手术治愈的病例(45例)中,入院时和出院时的平均体重分别为3750克和5177克;鼻十二指肠喂养的持续时间为8至37天(平均17.2天),鼻十二指肠喂养期间的平均体重增加为42.7克/天,平均住院时间为39.7天(43例无任何相关疾病的患者为38.0天)。这一经验表明,本报告中的鼻十二指肠喂养对于婴儿幽门狭窄而言是一种比任何传统医学治疗更有效的治疗方法,对于一小部分手术风险高或家长拒绝手术的患者而言,它可能是首选的治疗方法。

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本文引用的文献

1
Pyloric stenosis: selective medical and surgical treatment. A survey of sixteen years' experience.幽门狭窄:选择性药物与手术治疗。十六年经验综述。
Lancet. 1962 Jan 20;1(7221):119-21. doi: 10.1016/s0140-6736(62)91128-5.
2
CONGENITAL PYLORIC STENOSIS: A CONTROLLED EVALUATION OF MEDICAL TREATMENT UTILIZING METHYL-SCOPOLAMINE-NITRATE.先天性幽门狭窄:使用甲基东莨菪碱硝酸盐进行药物治疗的对照评估
J Pediatr. 1965 Mar;66:649-57. doi: 10.1016/s0022-3476(65)80128-7.
3
Hypertrophic pyloric stenosis in infancy treated with methyl scopolamine nitrate.
硝酸甲基东莨菪碱治疗婴儿肥厚性幽门狭窄
Arch Dis Child. 1955 Aug;30(152):377-86. doi: 10.1136/adc.30.152.377.
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Medical management of pyloric stenosis.幽门狭窄的医学管理。
JAMA. 1969 Feb 3;207(5):949-50. doi: 10.1001/jama.207.5.949.
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A nasojejunal tube for infant feeding.
Pediatrics. 1970 Jul;46(1):36-40.
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[Treatment of spastic, hypertrophic pyloric stenosis with methyl scopolamine nitrate].[硝酸甲基东莨菪碱治疗痉挛性肥厚性幽门狭窄]
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[Retrospective study of congenital hypertrophic pyloric stenosis and pylorospasm: Surgical vs. non-surgical treatment (author's transl)].先天性肥厚性幽门狭窄与幽门痉挛的回顾性研究:手术治疗与非手术治疗(作者译)
Monatsschr Kinderheilkd (1902). 1975 Jun;123(6):503-8.
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[Medical treatment of congenital pyloric stenosis. A review of treatment in a central hospital].[先天性幽门狭窄的医学治疗。一家中心医院的治疗回顾]
Ugeskr Laeger. 1975 Jan 20;137(4):201-3.
9
Induction of pyloric hypertrophy by pentagastrin. An animal model for infantile hypertrophic pyloric stenosis.五肽胃泌素诱导幽门肥大。婴儿肥厚性幽门狭窄的动物模型。
Gut. 1976 Apr;17(4):280-4. doi: 10.1136/gut.17.4.280.
10
Secretin, cholecystokinin and newer gastrointestinal hormones (first of two parts).促胰液素、缩胆囊素及新型胃肠激素(两部分中的第一部分)
N Engl J Med. 1976 May 13;294(20):1093-1101. doi: 10.1056/NEJM197605132942006.