癌胚抗原与γ-谷氨酰转肽酶联合用于研究结直肠癌的进展
Combination of carcinoembryonic antigen and gamma glutamyl transpeptidase in the study of the evolution of colorectal cancer.
作者信息
Steele L, Cooper E H, Mackay A M, Losowsky M S, Goligher J C
出版信息
Br J Cancer. 1974 Oct;30(4):319-24. doi: 10.1038/bjc.1974.199.
Abstract
Plasma CEA values and serum γ glutamyl transpeptidase activities have been compared in control subjects and 109 patients with colorectal carcinoma and 35 with non-malignant hepatic disease. CEA values alone differentiate hepatic metastases from non-malignant hepatic disease with a high degree of certainty. While CEA may be elevated with metastases, irrespective of site, γGT is elevated mainly in association with hepatic metastases. The combination of CEA and γGT is helpful in identifying hepatic metastases and in their differentiation from local recurrences or metastases to other sites.
摘要
对对照组、109例结直肠癌患者和35例非恶性肝病患者的血浆癌胚抗原（CEA）值和血清γ-谷氨酰转肽酶活性进行了比较。仅CEA值就能高度准确地区分肝转移和非恶性肝病。虽然无论转移部位如何，CEA可能会因转移而升高，但γGT主要在伴有肝转移时升高。CEA和γGT联合使用有助于识别肝转移，并将其与局部复发或转移至其他部位相区分。
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本文引用的文献
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