分离的胰岛中核苷磷酸化酶活性及肌苷刺激的胰岛素分泌的种属差异。
A species difference in nucleoside phosphorylase activity and inosine-stimulated insulin secretion in isolated islets of Langerhans.
作者信息
Campbell I L, Taylor K W
出版信息
Biochem J. 1977 Dec 15;168(3):591-3. doi: 10.1042/bj1680591.
Abstract
Inosine is a potent simulant of insulin release from rat but not from rabbit islets of Langerhans. Further investigation showed that nucleoside phosphorylase activity is exceptionally low in rabbit islets. The ability of inosine to promote insulin release seems to be related to islet nucleoside phosphorylase activity, which can display marked species differences.
摘要
肌苷是大鼠胰岛胰岛素释放的有效刺激物，但不是兔胰岛的。进一步研究表明，兔胰岛中的核苷磷酸化酶活性极低。肌苷促进胰岛素释放的能力似乎与胰岛核苷磷酸化酶活性有关，而该活性存在明显的物种差异。
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